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DNA Damage & Repair Compound Library

Catalog No. L3900
  Library Compound List   Excel SDF

A significant barrier to effective cancer therapy is the development of resistance to the drugs utilized, therefore, identifying new biological targets and designing new drugs becomes one of the most important strategies. Among the various potential targets, DNA damage and repair system in cancer cells is one of the most pivotal targets. The use of unspecific antibiotics to treat bacterial infections has caused a great deal of multiple resistant strains making less effective the current therapies with antibiotics. Developing inhibitors of DNA repair and related pathways in pathogens will have utility in the treatment of infections.

The TargetMol’s DNA Damage & Repair Compound Library, a unique collection of 937 DNA Damage & Repair related compounds, can be used for research in DNA damage and repair, and high throughput screening (HTS) and high content screening (HCS).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
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Product Description

  • A unique collection of 937 DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Targets include HDAC, DNA/RNA synthesis, Topoisomerase, etc.;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L3900)

Library Composition

DNA/RNA Synthesis (137)
HDAC (88)
PPAR (83)
Topoisomerase (70)
PARP (49)
Sirtuin (37)
CDK (33)
DNA-PK (31)
PI3K (29)
DUB (26)
ATM/ATR (23)
DNA Alkylation (21)
Microtubule Associated (20)
mTOR (19)
Aurora Kinase (15)
Casein Kinase (14)
Dehydrogenase (13)
Nucleoside Antimetabolite/Analog (12)
DHFR (12)
DNA gyrase (12)
Autophagy (11)
COX (11)
HSP (10)
Wnt/beta-catenin (10)
Antibacterial (10)
Reverse Transcriptase (9)
AChR (9)
Antifection (8)
ROCK (8)
Telomerase (8)
NF-κB (8)
Caspase (8)
P450 (7)
p53 (7)
HIV Protease (7)
PKC (7)
PERK (7)
GSK-3 (7)
Bcr-Abl (6)
Endogenous Metabolite (6)
Apoptosis (6)
Potassium Channel (6)
PLK (6)
PKA (6)
BCL (6)
HSV (6)
PDE (6)
ATPase (6)
DNA (6)
Epigenetic Reader Domain (6)
TNF (5)
GABA Receptor (5)
Src (5)
Deubiquitinase (5)
Antibiotic (5)
AMPK (5)
BMI-1 (5)
PDGFR (5)
LIM Kinase (4)
Chk (4)
Lipoxygenase (4)
IL Receptor (4)
Antiviral (4)
FLT (4)
VEGFR (4)
Vitamin (4)
Kinesin (4)
p97 (4)
MEK (4)
Akt (4)
ERK (4)
p38 MAPK (3)
Carbonic Anhydrase (3)
FGFR (3)
c-RET (3)
DNA Methyltransferase (3)
Mdm2 (3)
MAO (3)
Serine/threonin kinase (3)
Antifolate (3)
HCV Protease (3)
MTH1 (3)
Tyrosine Kinases (3)
MMP (3)
Tyrosinase (3)
Thrombin (3)
TGF-beta/Smad (3)
transporter (3)
HBV (3)
NMDAR (3)
Histamine Receptor (3)
Sodium Channel (3)
Nrf2 (3)
RAAS (3)
JNK (2)
GPR (2)
IRE1 (2)
Estrogen/progestogen Receptor (2)
IκB/IKK (2)
Adrenergic Receptor (2)
JAK (2)
Carboxypeptidase(CPG2) (2)
Influenza Virus (2)
EGFR (2)
P2 Receptor (2)
Trk receptor (2)
Arginase (2)
Transferase (2)
Retinoid Receptor (2)
ribosome (2)
NADPH (2)
SARS-CoV (2)
TLR (2)
MLK (2)
Adenosine Receptor (2)
ABC (2)
Cysteine Protease (2)
DNA Alkylator/Crosslinker (2)
KSP (1)
LDL (1)
MNK (1)
MPO (1)
MRP (1)
Mitochondrial Metabolism (1)
MicroRNA (1)
Liver X Receptor (1)
MAPK (1)
Wee1 (1)
LRRK2 (1)
Aminopeptidase (1)
IGF-1R (1)
Ras (1)
TAM Receptor (1)
Syk (1)
STAT (1)
SGK (1)
S6 Kinase (1)
ROS (1)
Rho (1)
Raf (1)
c-Fms (1)
Proteasome (1)
PI4K (1)
Aromatase (1)
Phospholipase (1)
PDK (1)
Parasite (1)
PAFR (1)
Cannabinoid Receptor (1)
Antioxidant (1)
cholecystokinin (1)
IDO (1)
GluR (1)
IAP (1)
Hydrogenase (1)
HIF (1)
HER (1)
Hedgehog/Smoothened (1)
Hck (1)
GRK (1)
Glucocorticoid Receptor (1)
c-Kit (1)
Gap Junction Protein (1)
Free radical scavengers (1)
Electron transport (1)
ALK (1)
Dopamine Receptor (1)
BTK (1)
Androgen Receptor (1)
c-Met/HGFR (1)
5-HT Receptor (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE