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FDA-Approved Kinase Inhibitor Library

Catalog No. L1610
  Library Compound List   Excel SDF

Kinases are a class of enzymes that facilitates phosphorylation, by transferring phosphate groups from high-energy donor molecules, such as ATP, to specific target molecules. A common group of kinases are the protein kinases, which act on specific proteins to phosphorylate them and alter their activity. Protein kinases are involved in a range of cell signaling and regulatory processes and play an important role in cell growth, metabolism, differentiation and apoptosis. Protein kinases have been associated with many diseases, including cancer, inflammatory diseases, cardiovascular diseases and neurological disorders. Therefore, targeting protein kinases has emerged as a promising therapeutic strategy for the treatment of related diseases.

Targetmol’s FDA-Approved Kinase Inhibitor Library contains 280 marketed drugs that target kinases. These kinases include Insulin/IGF Receptors、PI 3-Kinase、CaM Kinase II、JAK、PKA、CDK、JNK、PKC、CKI II、MAPK、RAF、EGFR、MEK、SAPK、GSK、MLCK、Src-family、IKK、PDGFR、VEGFR etc. FDA-Approved Kinase Inhibitor Library is a powerful tool for kinase drug development and related research.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Compound Libraries | TargetMol
Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com
Request Library
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Product Description

  • A unique collection of 266 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
  • All compounds have undergone preclinical studies and clinical trials, approved for marketing by FDA, EMA, PMDA, etc., with proven biological activity and safety.
  • Detailed instructions, compound structures, target information, IC50 values, activity descriptions, etc.
  • NMR, HPLC/LCMS and other assay techniques to ensure the correct structure and high purity of the product and reduce false positives.

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files
Request Library Compound List (L1610)

Publications Cited TargetMol Libraries

1. Cell Stem Cell. 2022 Apr 29(4) 545–558. 2. Science Bulletin. 2022. 3. Science Translational Medicine. 2022, 14(656): eabn3231. 4. Science Advances. 2023, 9(9): eade3760. 5. Nature. 2020, 582: 289-293. 6. Nature Biotechnology. 2021, 39(11): 1444-1452. 7. Nature Communications. 2022, 13(1): 1-15.. 8. Nature Communications. 2023, 14(1): 1020.. 9. Nature Communications. 2023, 14(1): 2756..
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Library Composition

Autophagy (72)
Apoptosis (57)
EGFR (36)
VEGFR (33)
c-Kit (32)
PDGFR (30)
JAK (18)
FLT (18)
FGFR (18)
Bcr-Abl (16)
Src (16)
Tyrosine Kinases (14)
c-Met/HGFR (14)
PKC (12)
CDK (12)
Raf (12)
ALK (11)
Antibacterial (10)
NF-κB (10)
Mitophagy (10)
CaMK (9)
PI3K (9)
AMPK (9)
c-RET (9)
Endogenous Metabolite (9)
Adrenergic Receptor (8)
Antibiotic (8)
mTOR (8)
BTK (8)
Sodium Channel (8)
Trk receptor (7)
TAM Receptor (7)
PKA (7)
Calcium Channel (7)
MEK (7)
5-HT Receptor (7)
Ferroptosis (7)
ERK (6)
ROCK (6)
Potassium Channel (6)
HER (6)
Akt (5)
ROS Kinase (5)
ROS (5)
HIV Protease (5)
PDE (5)
AChR (5)
Histamine Receptor (5)
COX (5)
Ras (5)
Parasite (5)
p38 MAPK (4)
P450 (4)
Dopamine Receptor (4)
GSK-3 (4)
Influenza Virus (4)
Antifungal (4)
Serine/threonin kinase (4)
IκB/IKK (4)
Glucosidase (3)
IGF-1R (3)
SARS-CoV (3)
Syk (3)
PAK (3)
c-Fms (3)
Topoisomerase (3)
FAK (3)
TOPK (3)
Glutathione Peroxidase (2)
Interleukin (2)
S1P Receptor (2)
DNA/RNA Synthesis (2)
MAPK (2)
PKM (2)
Adenosine Receptor (2)
P-gp (2)
Ligands for Target Protein for PROTAC (2)
Serine Protease (2)
LPL Receptor (2)
Ephrin Receptor (2)
Nrf2 (2)
Serotonin Transporter (2)
NADPH (2)
ROR (2)
TNF (2)
Tyrosinase (2)
Hexokinase (2)
Phosphatase (2)
Microtubule Associated (2)
Aurora Kinase (2)
IRE1 (2)
Lipoxygenase (2)
Proton pump (2)
NADPH-oxidase (1)
HIF/HIF Prolyl-Hydroxylase (1)
NO Synthase (1)
YAP (1)
Sigma receptor (1)
Transferase (1)
Dehydrogenase (1)
S6 Kinase (1)
DHFR (1)
Estrogen/progestogen Receptor (1)
Anti-infection (1)
DNA-PK (1)
HCV Protease (1)
Gap Junction Protein (1)
Hydroxylase (1)
PLK (1)
Integrin (1)
Hck (1)
HDAC (1)
CSF-1R (1)
Reactive Oxygen Species (1)
Monoamine Transporter (1)
Mitochondrial Metabolism (1)
Phosphorylase (1)
GRK (1)
LDL (1)
Virus Protease (1)
HSV (1)
Melatonin Receptor (1)
HBV (1)
TRP/TRPV Channel (1)
PPAR (1)
Caspase (1)
Nucleoside Antimetabolite/Analog (1)
gp120/CD4 (1)
IL Receptor (1)
Beta Amyloid (1)
IFNAR (1)
Antioxidant (1)
Sirtuin (1)
Antiviral (1)
AChE (1)
Antifolate (1)
ATP Citrate Lyase (1)
TGF-beta/Smad (1)
Chk (1)
Indoleamine 2,3-Dioxygenase (IDO) (1)
DNA (1)
JNK (1)
Norepinephrine (1)
GluR (1)
ACK (1)
PAD (1)
Chloride channel (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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