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Covalent Natural Product Library

Catalog No. L6150
  Library Compound List   Excel SDF

Natural products have been proven to demonstrate their success in modulating certain isolated but important targets, such as a range of antimicrobial targets, in particular protein-protein interactions. Therefore, many researchers consider natural products and their derivatives as unique tools for the study and manipulation of protein function.

Covalent compounds, a class of organic small molecules, can interact with specific target proteins and form covalent bonds, resulting in a change in protein conformation that inhibits protein activity. Except for some rare cases, protein modifications by covalent interactions are usually irreversible.

TargetMol Natural Product Covalent Library carefully screens 596 covalent compounds of natural products, which have not only the characteristics of natural products but also the mechanism of action of covalent compounds, and are cost-effective and powerful tools for drug development, pharmacological studies, stem cell differentiation, fingerprinting studies, quality studies and other fields.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Compound Libraries | TargetMol
Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM
250 μL * 10 mM
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com
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Product Description

  • Detialed biological information and pharmacological information of the products, providing theoretical direction and research basis for screening.
  • Clear source: a selection of known active natural products from animals, plants and microorganisms; specific to plant species, and labeled with accurate English and Latin names that facilitates later verification in your research.
  • Comprehensive information: Detailed descriptions from compound structure to solubility, from signaling pathways and targets to biological activity information.
  • Cost-effective: eliminates expensive natural products with poor drug-forming properties, allowing you to get more high-quality natural products at a lower cost.
  • Highly customizable with free combination according to natural product source, natural product category, research area, drug market status, etc.

Library Customization

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Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L6150)

Publications Cited TargetMol Libraries

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Library Composition

Endogenous Metabolite (111)
Apoptosis (91)
Antibacterial (69)
Autophagy (48)
NF-κB (43)
Antibiotic (43)
Reactive Oxygen Species (30)
Antifungal (24)
Antioxidant (19)
Influenza Virus (18)
COX (15)
HIV Protease (11)
Parasite (11)
Calcium Channel (10)
Dehydrogenase (10)
p38 MAPK (9)
ribosome (9)
STAT (9)
P450 (9)
Estrogen/progestogen Receptor (9)
GABA Receptor (9)
ERK (9)
Ferroptosis (9)
BCL (8)
TNF (8)
AChE (8)
MMP (8)
Akt (8)
ATPase (8)
Anti-infection (8)
NO Synthase (7)
AMPK (7)
Androgen Receptor (7)
ROS (7)
HSV (7)
Antiviral (7)
NOS (6)
PKC (6)
Caspase (6)
Glucocorticoid Receptor (6)
Microtubule Associated (6)
Progesterone Receptor (6)
HIF/HIF Prolyl-Hydroxylase (5)
Nrf2 (5)
Immunology/Inflammation related (5)
P-gp (5)
Mitophagy (5)
IL Receptor (5)
Wnt/beta-catenin (5)
SARS-CoV (5)
AChR (5)
Tyrosinase (5)
HBV (4)
DNA/RNA Synthesis (4)
Reductase (4)
Prostaglandin Receptor (4)
Virus Protease (4)
Lipoxygenase (4)
VEGFR (4)
Drug Metabolite (4)
HSP (4)
TRP/TRPV Channel (4)
Beta Amyloid (3)
Mitochondrial Metabolism (3)
Aromatase (3)
IκB/IKK (3)
JAK (3)
JNK (3)
CaMK (3)
Opioid Receptor (3)
HDAC (3)
Estrogen Receptor/ERR (3)
Epigenetic Reader Domain (3)
PPAR (3)
Sodium Channel (3)
EGFR (3)
Retinoid Receptor (3)
PI3K (3)
Proteasome (3)
Thrombin (2)
NMDAR (2)
PDE (2)
UGT (2)
p53 (2)
TGF-beta/Smad (2)
TLR (2)
Nucleoside Antimetabolite/Analog (2)
RAAS (2)
5-HT Receptor (2)
Interleukin (2)
FGFR (2)
Chloride channel (2)
HIF (2)
DNA Methyltransferase (2)
BACE (2)
iGluR (2)
Adrenergic Receptor (2)
Antifolate (2)
MAPK (2)
MAO (2)
RAR/RXR  (1)
Ras (1)
Sirtuin (1)
RANKL/RANK (1)
FAK (1)
Raf (1)
Dopamine Receptor (1)
DNA gyrase (1)
CRISPR/Cas9 (1)
Serine Protease (1)
Telomerase (1)
Smo (1)
c-Met/HGFR (1)
Src (1)
Pyroptosis (1)
CDK (1)
CAT (1)
Beta-Secretase (1)
Topoisomerase (1)
Transaminase (1)
Transferase (1)
Aurora Kinase (1)
Tyrosine Kinases (1)
Antifection (1)
Acyltransferase (1)
Free radical scavengers (1)
Mdm2 (1)
PTEN (1)
PARP (1)
Monoamine Oxidase (1)
Monoamine Transporter (1)
mTOR (1)
Lipid (1)
ABC (1)
Integrin (1)
Indoleamine 2,3-Dioxygenase (IDO) (1)
IAP (1)
Histone Methyltransferase (1)
Histone Acetyltransferase (1)
Oxytocin Receptor (1)
Histamine Receptor (1)
HER (1)
Hedgehog/Smoothened (1)
PD-1/PD-L1 (1)
Proton pump (1)
HCV Protease (1)
PDGFR (1)
PGE Synthase (1)
GSK-3 (1)
Phosphatase (1)
Phospholipase (1)
Glutathione reductase (1)
PKA (1)
GluR (1)
PKM (1)
Potassium Channel (1)
Glucosidase (1)
Glucagon Receptor (1)
Gamma-secretase (1)
FXR (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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