FDA-Approved & Pharmacopeia Drug Library

Catalog No. L1010

Library Compound List Excel SDF

Traditional de novo drug discovery and development involves an HTS campaign for de novo candidate hits and requires highly specialized screening facilities and compound libraries containing several million compounds. It is a time consuming and expensive process. As the regulation for drug safety and efficacy is increasingly getting complex, the cost of developing new drugs is keeping skyrocket. Drug repositioning, also known as old drugs for new uses, is an effective strategy to find new indications for existing drugs and has recently drawn attention and has led to several blockbuster drugs because of its high efficiency and low-cost. High-content screens, new biomarkers, noninvasive imaging techniques, and advanced in bioinformatics have created new opportunities for pursuing novel indications for approved compounds.

Approved drugs all have known and well-characterized bioactivities, safety and bioavailability – properties which could dramatically accelerate drug development and optimization. Hits from this set will provide a significant head start in any drug optimization program. In addition, a growing number of compounds have been identified from this library that can functionally replace reprogramming transcription factors, enhance efficiency of iPSC generation and accelerate the reprogramming process by single use or a combination of several molecules.

TargetMol’s FDA-Approved & Pharmacopeia Drug Library collects 3158 compounds from approved institutions such as FDA, EMA, PMDA, NMPA, etc. or pharmacopoeia such as USP, BP, JP, etc., which can be used for drug repositioning and cell induction.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)

Request for Quote

If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com

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Product Description

3158 compounds from marketed drugs for high throughput screening (HTS) and high content screening (HCS);
All compounds collected in this library are drugs approved by FDA, EMA, PMDA, NMPA, etc. or included in pharmacopoeia such as USP, BP, JP, etc.;
An effective tool for discovering new with old drugs and new drug target identification;
Covers various research areas, such as Cancer, Cardiovascular disease, Neuroscience, Immunology/Inflammation, respiratory system disease, etc.
More detailed compound information with structure, target, activity, IC50 value, and brief introduction;
Structurally diverse, medicinally active, and cell permeable;
NMR and HPLC validated to ensure high purity and quality.

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files

Publications Cited TargetMol Libraries

1. Antiviral Research. 2022: 105417. 2. International Journal of Molecular Medicine. 2023, 51(6): 1-13. 3. Cell Stem Cell. 2022 Apr 29(4) 545–558. 4. Science Bulletin. 2022. 5. Science Translational Medicine. 2022, 14(656): eabn3231. 6. Science Advances. 2023, 9(9): eade3760. 7. Nature. 2020, 582: 289-293. 8. Nature Biotechnology. 2021, 39(11): 1444-1452. 9. Nature Communications. 2022, 13(1): 1-15..

10. Nature Communications. 2023, 14(1): 1020.. 11. Nature Communications. 2023, 14(1): 2756.. 12. Blood. 2021, 137(11): 1478-1490. 13. Nucleic Acids Research. 2021. 14. Nature Communications. 2023, 14(1): 7574. 15. Advanced Science. 2020, 7(16): 2000925. 16. Angewandte Chemie. 2021. 17. Acta Pharmaceutica Sinica B. 2022. 18. Protein & Cell. 2021, 12(11): 877-888. 19. Bone Research. 2023, 11(1): 54. 20. Pharmacology & Therapeutics. (2021): 107930. 21. Nature Communications. 2021, 12(1): 1-12. 22. Journal of Cell Biology. 2022, 221(5): e202112024.

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Library Composition

Antibacterial (470)

Antibiotic (424)

Autophagy (360)

Endogenous Metabolite (315)

Apoptosis (294)

5-HT Receptor (169)

Adrenergic Receptor (165)

AChR (144)

COX (135)

Parasite (133)

Histamine Receptor (115)

Dopamine Receptor (112)

Antifungal (109)

HIV Protease (91)

Calcium Channel (84)

Sodium Channel (84)

DNA/RNA Synthesis (81)

Potassium Channel (79)

NF-κB (58)

Topoisomerase (54)

Reactive Oxygen Species (52)

Estrogen/progestogen Receptor (51)

P450 (51)

Influenza Virus (51)

Glucocorticoid Receptor (47)

Ferroptosis (47)

SARS-CoV (45)

PDE (45)

RAAS (41)

GABA Receptor (41)

Dehydrogenase (39)

Mitophagy (36)

EGFR (35)

VEGFR (34)

HCV Protease (33)

HSV (32)

ribosome (32)

c-Kit (32)

Serotonin Transporter (30)

PPAR (30)

PDGFR (30)

AChE (29)

Microtubule Associated (29)

Nucleoside Antimetabolite/Analog (29)

Prostaglandin Receptor (29)

Reverse Transcriptase (28)

Estrogen Receptor/ERR (28)

Virus Protease (27)

MAO (27)

Progesterone Receptor (26)

Norepinephrine (24)

Antioxidant (24)

HBV (24)

Proteasome (23)

iGluR (22)

ATPase (22)

Antifection (22)

FGFR (20)

TNF (20)

TRP/TRPV Channel (19)

HDAC (19)

Androgen Receptor (19)

JAK (19)

Monoamine Oxidase (19)

Carbonic Anhydrase (19)

Proton pump (19)

MMP (18)

FLT (18)

Opioid Receptor (18)

Thrombin (17)

PKC (17)

Phosphatase (16)

ROS (16)

Adenosine Receptor (16)

Transferase (16)

Src (16)

Bcr-Abl (16)

DNA Alkylator/Crosslinker (16)

c-Met/HGFR (15)

IL Receptor (15)

Antiviral (15)

Tyrosine Kinases (15)

DPP-4 (15)

Drug Metabolite (14)

NMDAR (14)

HIF/HIF Prolyl-Hydroxylase (14)

GluR (14)

CDK (13)

Lipoxygenase (13)

PI3K (13)

NO Synthase (13)

MRP (13)

Raf (12)

HMG-CoA Reductase (12)

AMPK (12)

Phospholipase (12)

ERK (12)

Tyrosinase (12)

GNRH Receptor (12)

Retinoid Receptor (12)

Interleukin (11)

DHFR (11)

Thyroid hormone receptor(THR) (11)

SGLT (11)

STAT (11)

P-gp (11)

ALK (11)

Amino Acids and Derivatives (11)

Beta Amyloid (11)

Antifolate (11)

PARP (11)

Akt (10)

Mitochondrial Metabolism (10)

mTOR (10)

Nrf2 (10)

BTK (9)

CaMK (9)

c-RET (9)

DNA Alkylation (9)

MEK (9)

Factor Xa (9)

DNA gyrase (9)

HER (8)

ABC (8)

P2Y Receptor (8)

Serine Protease (8)

CAT (8)

Chloride channel (8)

p38 MAPK (8)

TLR (8)

Cysteine Protease (7)

DNA Methyltransferase (7)

Neurokinin receptor (7)

TAM Receptor (7)

Monoamine Transporter (7)

PKA (7)

S1P Receptor (7)

CFTR (7)

GPR (7)

Trk receptor (7)

NADPH (7)

Hedgehog/Smoothened (6)

BCL (6)

IκB/IKK (6)

Glutathione Peroxidase (6)

Caspase (6)

TGF-beta/Smad (6)

Histone Methyltransferase (6)

ROCK (6)

HSP (6)

LPL Receptor (6)

Endothelin Receptor (6)

P2X Receptor (6)

Reductase (6)

Lipid (5)

GSK-3 (5)

Xanthine Oxidase (5)

HIF (5)

DNA (5)

Hydroxylase (5)

PGE Synthase (5)

Integrin (5)

Vasopressin Receptor (5)

Serine/threonin kinase (5)

Wnt/beta-catenin (5)

ROS Kinase (5)

FAK (5)

Annexin A (5)

Ras (5)

CaSR (5)

FXR (5)

Guanylate cyclase (5)

Anti-infection (5)

Fatty Acid Synthase (5)

Smo (4)

Neprilysin (4)

Cannabinoid Receptor (4)

Aryl Hydrocarbon Receptor (4)

NOS (4)

NOD-like Receptor (NLR) (4)

Sigma receptor (4)

GPCR19 (4)

Oxytocin Receptor (4)

UGT (4)

Imidazoline Receptor (4)

Gamma-secretase (4)

NOD (4)

MT Receptor (4)

Histone Demethylase (4)

Cell wall (4)

AhR (4)

Melatonin Receptor (4)

Decarboxylase (4)

p53 (3)

Aromatase (3)

Free radical scavengers (3)

CETP (3)

Leukotriene Receptor (3)

c-Fms (3)

Ligand for E3 Ligase (3)

Aminopeptidase (3)

Sirtuin (3)

cholecystokinin (3)

PKM (3)

Adenosine deaminase (3)

CCR (3)

PAK (3)

Gap Junction Protein (3)

Isocitrate Dehydrogenase (IDH) (3)

GST (3)

Aurora Kinase (3)

Molecular Glues (3)

GluCls (3)

Syk (3)

IGF-1R (3)

Hexokinase (3)

Glucosidase (3)

Na-K-Cl cotransporter (3)

LDL (3)

JNK (3)

Protease-activated Receptor (2)

Melanocortin Receptor (2)

ROR (2)

PDK (2)

Complement System (2)

S6 Kinase (2)

Monocarboxylate transporter (2)

PLK (2)

CGRP Receptor (2)

Platelet aggregation (2)

DUB (2)

RSV (2)

YAP (2)

Integrase (2)

LTR (2)

IFNAR (2)

CXCR (2)

Adiponectin receptor (2)

IRE1 (2)

Somatostatin (2)

Immunology/Inflammation related (2)

Thrombopoietin Receptor (2)

Epigenetic Reader Domain (2)

Indoleamine 2,3-Dioxygenase (IDO) (2)

GlyT (2)

DYRK (2)

Telomerase (2)

Phosphorylase (2)

Arginase (2)

Ligands for Target Protein for PROTAC (2)

TOPK (2)

CRM1 (2)

OAT (2)

Ephrin Receptor (2)

Rho (2)

MAPK (2)

Glutathione reductase (2)

Beta-Secretase (2)

IRAK (1)

Glucagon Receptor (1)

GRK (1)

MTH1 (1)

PAFR (1)

gp120/CD4 (1)

N-Acetylglucosaminyltransferase (1)

IAP (1)

PD-1/PD-L1 (1)

Myosin (1)

Hck (1)

Glucokinase (1)

CSF-1R (1)

BACE (1)

Mdm2 (1)

Liver X Receptor (1)

Lipase (1)

RANKL/RANK (1)

RAR/RXR (1)

FAAH (1)

NADPH-oxidase (1)

cAMP (1)

Pyroptosis (1)

Dynamin (1)

transporter (1)

Histone Acetyltransferase (1)

DNA-PK (1)

STING (1)

Acyltransferase (1)

CRISPR/Cas9 (1)

ATP Citrate Lyase (1)

GHSR (1)

Hydrogenase (1)

Aquaporin (1)

ACK (1)

Na+/Ca2+ Exchanger (1)

NPC1L1 (1)

Epoxide Hydrolase (1)

PAD (1)

OX Receptor (1)

Chk (1)

Angiotensin-converting Enzyme (ACE) (1)

Bradykinin Receptor (1)

Casein Kinase (1)

advanced glycation end products (1)

PROTAC Linker (1)

Anion Exchanger (1)

Taste receptor (1)

VDA (1)

Library Information Sample

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty