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Anti-CCL2 Monoclonal Antibody-AF488
Anti-CCL2 Monoclonal Antibody-AF488
Anti-CCL2 Monoclonal Antibody-AF488 is a biotin-conjugated rabbit antibody targeting CCL2. Anti-CCL2 Monoclonal Antibody-AF488 can be used in ELISA, FACS.
Catalog No. TMAZ-0376A4
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Anti-CCL2 Monoclonal Antibody-AF488
Catalog No. TMAZ-0376A4
Anti-CCL2 Monoclonal Antibody-AF488 is a biotin-conjugated rabbit antibody targeting CCL2. Anti-CCL2 Monoclonal Antibody-AF488 can be used in ELISA, FACS.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. 
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Bioactivity
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Antigen Details
Chemical Properties
| Description | Anti-CCL2 Monoclonal Antibody-AF488 is a biotin-conjugated rabbit antibody targeting CCL2. Anti-CCL2 Monoclonal Antibody-AF488 can be used in ELISA, FACS. |
| Alias | C-C motif chemokine 2, Monocyte secretory protein JE, Monocyte chemotactic protein 1, HC11, Small-inducible cytokine A2, Monocyte chemotactic and activating factor, Monocyte chemoattractant protein 1 |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of CCL2 overexpressed 446F cells with TMAZ-0376A4, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | ELISA, FACS |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Single-pass type I membrane |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of CCL2 protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Acts as a ligand for C-C chemokine receptor CCR2 (PubMed:10529171, PubMed:10587439, PubMed:9837883). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (PubMed:10587439, PubMed:9837883). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (PubMed:8195247, PubMed:8627182, PubMed:9792674). May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis (PubMed:8107690) |
| Others Formats | Biotin/APC/PE/AF555/AF647 |
| Antibody Types Available | 1 |
| Immunogen | CCL2 |
| Antigen Species | Human |
| Gene ID | 6347 |
| Uniprot ID | |
| Biology Area | Cancer Research |
| Molecular Weight | 150 kDa |
Stability & Storage
| Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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