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Anti-CCL2 Monoclonal Antibody-APC
Catalog No. TMAZ-0376A
Alias Small-inducible cytokine A2, Monocyte secretory protein JE, Monocyte chemotactic protein 1, Monocyte chemotactic and activating factor, Monocyte chemoattractant protein 1, HC11, C-C motif chemokine 2
Anti-CCL2 Monoclonal Antibody-APC is a biotin-conjugated rabbit antibody targeting CCL2. Anti-CCL2 Monoclonal Antibody-APC can be used in ELISA, FACS.
Anti-CCL2 Monoclonal Antibody-APC
Anti-CCL2 Monoclonal Antibody-APC
Catalog No. TMAZ-0376AAlias Small-inducible cytokine A2, Monocyte secretory protein JE, Monocyte chemotactic protein 1, Monocyte chemotactic and activating factor, Monocyte chemoattractant protein 1, HC11, C-C motif chemokine 2
Anti-CCL2 Monoclonal Antibody-APC is a biotin-conjugated rabbit antibody targeting CCL2. Anti-CCL2 Monoclonal Antibody-APC can be used in ELISA, FACS.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 μg | $570 | 12 days | |
| 50 μg | $945 | 12 days | |
| 100 μg | $1,415 | 12 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CCL2 Monoclonal Antibody-APC is a biotin-conjugated rabbit antibody targeting CCL2. Anti-CCL2 Monoclonal Antibody-APC can be used in ELISA, FACS. |
| Alias | Small-inducible cytokine A2, Monocyte secretory protein JE, Monocyte chemotactic protein 1, Monocyte chemotactic and activating factor, Monocyte chemoattractant protein 1, HC11, C-C motif chemokine 2 |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of CCL2 overexpressed 446F cells with TMAZ-0376A, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | ELISA, FACS |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Single-pass type I membrane |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of CCL2 protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Acts as a ligand for C-C chemokine receptor CCR2 (PubMed:10529171, PubMed:10587439, PubMed:9837883). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (PubMed:10587439, PubMed:9837883). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (PubMed:8195247, PubMed:8627182, PubMed:9792674). May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis (PubMed:8107690) |
| Others Formats | Biotin/PE/AF488/AF555/AF647 |
| Antibody Types Available | 1 |
| Immunogen | CCL2 |
| Antigen Species | Human |
| Gene ID | 6347 |
| Uniprot ID | |
| Biology Area | Cancer Research |
| Molecular Weight | 150 kDa |
Stability & Storage
| Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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