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Anti-CD38 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting CD38. Anti-CD38 Monoclonal Antibody-AF488 can be used in ELISA, FACS.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 μg | $485 | 12 days | |
50 μg | $805 | 12 days | |
100 μg | $1,205 | 12 days |
Description | Anti-CD38 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting CD38. Anti-CD38 Monoclonal Antibody-AF488 can be used in ELISA, FACS. |
Alias | T10, Cyclic ADP-ribose hydrolase 1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, ADP-ribosyl cyclase 1, 2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-ADP-ribosyl cyclase |
Ig Type | Rabbit monoclonal IgG |
Reactivity | Human |
Verified Activity | Flow cytometry analysis of CD38 overexpressed 396F cells with TMAZ-0014A4, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
Application | ELISA, FACS |
Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Subcellular Localization | Single-pass type I membrane |
Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of CD38 protein. |
Purification | Protein A Affinity Purified |
Appearance | Liquid |
Formulation | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
Purity | > 95% as determined by SDS-PAGE. |
Research Background | Synthesizes cyclic ADP-ribose (cADPR), a second messenger for glucose-induced insulin secretion (PubMed: 7961800, PubMed: 8253715). Synthesizes the Ca(2+) mobilizer nicotinate-adenine dinucleotide phosphate, NAADP(+), from 2'-phospho-cADPR and nicotinic acid, as well as from NADP(+) and nicotinic acid. At both pH 5.0 and pH 7.4 preferentially transforms 2'-phospho-cADPR into NAADP(+), while preferentially cleaving NADP(+) to cADPR and ADPRP rather than into NADDP(+) (PubMed: 16690024). Has cADPR hydrolase activity (PubMed: 7961800, PubMed: 8253715) |
Conjucates | AF488 |
Others Formats | Biotin/APC/PE/AF555/AF647 |
Antibody Types Available | 2 |
Immunogen | CD38 |
Antigen Species | Human |
Gene ID | 952 |
Uniprot ID | |
Biology Area | Immunology Research |
Molecular Weight | 150 kDa |
Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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