Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-CD82 Monoclonal Antibody-AF647
😃Good
Catalog No. TMAZ-0048A6
Alias Tetraspanin-27, Suppressor of tumorigenicity 6 protein, Metastasis suppressor Kangai-1, Inducible membrane protein R2, IA4, CD82 antigen, C33 antigen
Anti-CD82 Monoclonal Antibody-AF647 is a Biotin-conjugated rabbit antibody targeting CD82. Anti-CD82 Monoclonal Antibody-AF647 can be used in ELISA, FACS.
Anti-CD82 Monoclonal Antibody-AF647
Anti-CD82 Monoclonal Antibody-AF647
😃Good
Catalog No. TMAZ-0048A6Alias Tetraspanin-27, Suppressor of tumorigenicity 6 protein, Metastasis suppressor Kangai-1, Inducible membrane protein R2, IA4, CD82 antigen, C33 antigen
Anti-CD82 Monoclonal Antibody-AF647 is a Biotin-conjugated rabbit antibody targeting CD82. Anti-CD82 Monoclonal Antibody-AF647 can be used in ELISA, FACS.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 μg | $340 | 12 days | |
| 50 μg | $560 | 12 days | |
| 100 μg | $840 | 12 days |
Bulk & Custom
Add to Cart
Questions
View MoreContact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD82 Monoclonal Antibody-AF647 is a Biotin-conjugated rabbit antibody targeting CD82. Anti-CD82 Monoclonal Antibody-AF647 can be used in ELISA, FACS. |
| Alias | Tetraspanin-27, Suppressor of tumorigenicity 6 protein, Metastasis suppressor Kangai-1, Inducible membrane protein R2, IA4, CD82 antigen, C33 antigen |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of CD82 overexpressed 293F cells with TMAZ-0048A6BI, which was counjucated with SA-PE (red). The WT 293F control is black line. |
| Application | ELISA, FACS |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Single-pass type I membrane |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of CD82 protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling (PubMed: 19497983). Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Acts as a attenuator of EGF signaling, facilitating ligand-induced endocytosis of the receptor and its subsequent desensitization (PubMed: 10985391, PubMed: 35538033). Mechanistically, modulates ligand-induced ubiquitination and trafficking of EGFR via E3 ligase CBL phosphorylation by PKC (PubMed: 23897813). Increases cell-matrix adhesion by regulating the membrane organization of integrin alpha4/ITA4 (PubMed: 24623721, PubMed: 8757325). Modulates adhesion and suppresses cell migration through other integrins such as the alpha6/ITGA6 and beta1/ITGB1 (PubMed: 15557282, PubMed: 17560548). Decreases cell-associated plasminogen activation by interfering with the interaction between urokinase-type plasminogen activator/PLAU and its receptor PLAUR (PubMed: 15677461). Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway. Plays a role in TLR9 trafficking to acidified CpG-containing compartments by controlling interaction between TLR9 and VAMP3 and subsequent myddosome assembly (By similarity). Inhibits LPS-induced inflammatory response by preventing binding of LPS to TLR4 on the cell surface (PubMed: 36945827). Plays a role in the activation of macrophages into anti-inflammatory phenotypes (By similarity). Independently of Toll-like receptor (TLR) signaling, is recruited to pathogen-containing phagosomes prior to fusion with lysosomes and thereby participates in antigen presentation (By similarity). Acts also to control angiogenesis and switch angiogenic milieu to quiescent state by binding and sequestering VEGFA and PDGFB to inhibit the signaling they trigger via their respective cell surface receptor (PubMed: 34530889) |
| Conjucates | AF647 |
| Others Formats | Biotin/APC/PE/AF488/AF555 |
| Antibody Types Available | 1 |
| Immunogen | CD82 |
| Antigen Species | Human |
| Gene ID | 3732 |
| Uniprot ID | |
| Biology Area | Immunology Research |
| Molecular Weight | 150 kDa |
Stability & Storage
| Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-CD82 Monoclonal Antibody-AF647 | purchase Anti-CD82 Monoclonal Antibody-AF647 | Anti-CD82 Monoclonal Antibody-AF647 cost | order Anti-CD82 Monoclonal Antibody-AF647 | Anti-CD82 Monoclonal Antibody-AF647 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.