Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-EFNA1 Monoclonal Antibody-APC

😃Good
Catalog No. TMAZ-0208A
Alias Tumor necrosis factor alpha-induced protein 4, Immediate early response protein B61, Ephrin-A1, EPH-related receptor tyrosine kinase ligand 1

Anti-EFNA1 Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting EFNA1. Anti-EFNA1 Monoclonal Antibody-APC can be used in ELISA, FACS.

Anti-EFNA1 Monoclonal Antibody-APC

Anti-EFNA1 Monoclonal Antibody-APC

😃Good
Catalog No. TMAZ-0208AAlias Tumor necrosis factor alpha-induced protein 4, Immediate early response protein B61, Ephrin-A1, EPH-related receptor tyrosine kinase ligand 1
Anti-EFNA1 Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting EFNA1. Anti-EFNA1 Monoclonal Antibody-APC can be used in ELISA, FACS.
Pack SizePriceAvailabilityQuantity
25 μg$57012 days
50 μg$94512 days
100 μg$1,41512 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anti-EFNA1 Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting EFNA1. Anti-EFNA1 Monoclonal Antibody-APC can be used in ELISA, FACS.
AliasTumor necrosis factor alpha-induced protein 4, Immediate early response protein B61, Ephrin-A1, EPH-related receptor tyrosine kinase ligand 1
Ig Type
Rabbit monoclonal IgG
Reactivity
Human
Verified Activity
Flow cytometry analysis of EFNA1 overexpressed 436F cells with TMAZ-0208A, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
Application
ELISA, FACS
Recommended Dose
0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted
ConstructionThis antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of EFNA1 protein.
PurificationProtein A Affinity Purified
AppearanceLiquid
Formulation0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin.
Purity> 95% as determined by SDS-PAGE.
Research BackgroundCell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Plays an important role in angiogenesis and tumor neovascularization. The recruitment of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. Exerts anti-oncogenic effects in tumor cells through activation and down-regulation of EPHA2. Activates EPHA2 by inducing tyrosine phosphorylation which leads to its internalization and degradation. Acts as a negative regulator in the tumorigenesis of gliomas by down-regulating EPHA2 and FAK. Can evoke collapse of embryonic neuronal growth cone and regulates dendritic spine morphogenesis
Related Conjugates and Formulations
Conjucates
APC
Others Formats
Biotin/PE/AF488/AF555/AF647
Antibody Types Available
2
Antigen Details
Immunogen
EFNA1
Antigen Species
Human
Gene ID
1942
Uniprot ID
Biology Area
Cytokines
Chemical Properties
Molecular Weight150 kDa
Stability & Storage
Stability & StorageFor unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze.
TransportFor unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-EFNA1 Monoclonal Antibody-APC | purchase Anti-EFNA1 Monoclonal Antibody-APC | Anti-EFNA1 Monoclonal Antibody-APC cost | order Anti-EFNA1 Monoclonal Antibody-APC | Anti-EFNA1 Monoclonal Antibody-APC molecular weight