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Anti-IL1R1 Monoclonal Antibody-AF488
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Catalog No. TMAZ-0067A4
Alias p80, Interleukin-1 receptor type I, Interleukin-1 receptor type 1, Interleukin-1 receptor alpha, CD121 antigen-like family member A
Anti-IL1R1 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting IL1R1. Anti-IL1R1 Monoclonal Antibody-AF488 can be used in ELISA, FACS.
Anti-IL1R1 Monoclonal Antibody-AF488
Anti-IL1R1 Monoclonal Antibody-AF488
😃Good
Catalog No. TMAZ-0067A4Alias p80, Interleukin-1 receptor type I, Interleukin-1 receptor type 1, Interleukin-1 receptor alpha, CD121 antigen-like family member A
Anti-IL1R1 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting IL1R1. Anti-IL1R1 Monoclonal Antibody-AF488 can be used in ELISA, FACS.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 μg | 541 € | 12 days | |
| 50 μg | 897 € | 12 days | |
| 100 μg | 1.344 € | 12 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-IL1R1 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting IL1R1. Anti-IL1R1 Monoclonal Antibody-AF488 can be used in ELISA, FACS. |
| Alias | p80, Interleukin-1 receptor type I, Interleukin-1 receptor type 1, Interleukin-1 receptor alpha, CD121 antigen-like family member A |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of IL1R1 overexpressed 483F cells with TMAZ-0067A4, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | ELISA, FACS |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Single-pass membrane protein |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of IL1R1 protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Receptor for IL1A, IL1B and IL1RN (PubMed: 2950091, PubMed: 37315560). After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells (PubMed: 10653850) |
| Conjucates | AF488 |
| Others Formats | Biotin/APC/PE/AF555/AF647 |
| Antibody Types Available | 1 |
| Immunogen | IL1R1 |
| Antigen Species | Human |
| Gene ID | 3554 |
| Uniprot ID | |
| Biology Area | Immunology Research |
| Molecular Weight | 150 kDa |
Stability & Storage
| Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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