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Anti-KIR3DL2 Monoclonal Antibody-AF488

Anti-KIR3DL2 Monoclonal Antibody-AF488
Anti-KIR3DL2 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting KIR3DL2. Anti-KIR3DL2 Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF.
Catalog No. TMAZ-0179A4

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Anti-KIR3DL2 Monoclonal Antibody-AF488

Catalog No. TMAZ-0179A4Alias p70 natural killer cell receptor clone CL-5, Natural killer-associated transcript 4, Killer cell immunoglobulin-like receptor 3DL2, CD158 antigen-like family member K

Anti-KIR3DL2 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting KIR3DL2. Anti-KIR3DL2 Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF.
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25 μgInquiry12 days
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100 μgInquiry12 days
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Product Introduction

Bioactivity
Description
Anti-KIR3DL2 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting KIR3DL2. Anti-KIR3DL2 Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF.
Aliasp70 natural killer cell receptor clone CL-5, Natural killer-associated transcript 4, Killer cell immunoglobulin-like receptor 3DL2, CD158 antigen-like family member K
Ig Type
Rabbit monoclonal IgG
Reactivity
Human
Verified Activity
Flow cytometry analysis of KIR3DL2 overexpressed 354F cells with TMAZ-0179A4, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
Application
ELISA, FACS, IF
Recommended Dose
0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted
ConstructionThis antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of KIR3DL2 protein.
PurificationProtein A Affinity Purified
AppearanceLiquid
Formulation0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin.
Purity> 95% as determined by SDS-PAGE.
Research BackgroundReceptor on natural killer (NK) cells and T cells for MHC class I molecules (PubMed: 24018270, PubMed: 28636952). Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions (PubMed: 24018270). Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity (PubMed: 26928464)
Related Conjugates and Formulations
Conjucates
AF488
Others Formats
Biotin/APC/PE/AF555/AF647
Antibody Types Available
3
Antigen Details
Immunogen
KIR3DL2
Antigen Species
Human
Gene ID
3812
Uniprot ID
Biology Area
Drug Target
Chemical Properties
Molecular Weight150 kDa
Stability & Storage
Stability & StorageFor unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze.
TransportFor unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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