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Anti-KIR3DL2 Monoclonal Antibody-APC
Catalog No. TMAZ-0179A
Alias p70 natural killer cell receptor clone CL-5, Natural killer-associated transcript 4, Killer cell immunoglobulin-like receptor 3DL2, CD158 antigen-like family member K
Anti-KIR3DL2 Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting KIR3DL2. Anti-KIR3DL2 Monoclonal Antibody-APC can be used in ELISA, FACS, IF.
Anti-KIR3DL2 Monoclonal Antibody-APC
Anti-KIR3DL2 Monoclonal Antibody-APC
Catalog No. TMAZ-0179AAlias p70 natural killer cell receptor clone CL-5, Natural killer-associated transcript 4, Killer cell immunoglobulin-like receptor 3DL2, CD158 antigen-like family member K
Anti-KIR3DL2 Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting KIR3DL2. Anti-KIR3DL2 Monoclonal Antibody-APC can be used in ELISA, FACS, IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 μg | $570 | 12 days | |
| 50 μg | $945 | 12 days | |
| 100 μg | $1,415 | 12 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-KIR3DL2 Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting KIR3DL2. Anti-KIR3DL2 Monoclonal Antibody-APC can be used in ELISA, FACS, IF. |
| Alias | p70 natural killer cell receptor clone CL-5, Natural killer-associated transcript 4, Killer cell immunoglobulin-like receptor 3DL2, CD158 antigen-like family member K |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of KIR3DL2 overexpressed 354F cells with TMAZ-0179A, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | ELISA, FACS, IF |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of KIR3DL2 protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Receptor on natural killer (NK) cells and T cells for MHC class I molecules (PubMed: 24018270, PubMed: 28636952). Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions (PubMed: 24018270). Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity (PubMed: 26928464) |
| Conjucates | APC |
| Others Formats | Biotin/PE/AF488/AF555/AF647 |
| Antibody Types Available | 3 |
| Immunogen | KIR3DL2 |
| Antigen Species | Human |
| Gene ID | 3812 |
| Uniprot ID | |
| Biology Area | Drug Target |
| Molecular Weight | 150 kDa |
Stability & Storage
| Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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