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Anti-KLK8 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting KLK8. Anti-KLK8 Monoclonal Antibody-AF488 can be used in ELISA, FACS.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 μg | $570 | 12 days | |
50 μg | $945 | 12 days | |
100 μg | $1,415 | 12 days |
Description | Anti-KLK8 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting KLK8. Anti-KLK8 Monoclonal Antibody-AF488 can be used in ELISA, FACS. |
Alias | Tumor-associated differentially expressed gene 14 protein, Serine protease TADG-14, Serine protease 19, Ovasin, Neuropsin, Kallikrein-8 |
Ig Type | Rabbit monoclonal IgG |
Reactivity | Human |
Verified Activity | Flow cytometry analysis of KLK8 overexpressed 475F cells with TMAZ-0264A4, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
Application | ELISA, FACS |
Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Subcellular Localization | Secreted |
Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of KLK8 protein. |
Purification | Protein A Affinity Purified |
Appearance | Liquid |
Formulation | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
Purity | > 95% as determined by SDS-PAGE. |
Research Background | Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte proliferation. Plays a role in the secondary phase of pathogenesis following spinal cord injury |
Conjucates | AF488 |
Others Formats | Biotin/APC/PE/AF555/AF647 |
Antibody Types Available | 1 |
Immunogen | KLK8 |
Antigen Species | Human |
Gene ID | 11202 |
Uniprot ID | |
Biology Area | Other Functions |
Molecular Weight | 150 kDa |
Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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