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Anti-MADCAM1 Monoclonal Antibody-AF488
Anti-MADCAM1 Monoclonal Antibody-AF488
Anti-MADCAM1 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting MADCAM1. Anti-MADCAM1 Monoclonal Antibody-AF488 can be used in ELISA, FACS.
Catalog No. TMAZ-0169A4
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Anti-MADCAM1 Monoclonal Antibody-AF488
Catalog No. TMAZ-0169A4Alias Mucosal addressin cell adhesion molecule 1
Anti-MADCAM1 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting MADCAM1. Anti-MADCAM1 Monoclonal Antibody-AF488 can be used in ELISA, FACS.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 μg | Inquiry | 12 days | |
| 50 μg | Inquiry | 12 days | |
| 100 μg | Inquiry | 12 days |
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Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-MADCAM1 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting MADCAM1. Anti-MADCAM1 Monoclonal Antibody-AF488 can be used in ELISA, FACS. |
| Alias | Mucosal addressin cell adhesion molecule 1 |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of MADCAM1 overexpressed 381F cells with TMAZ-0169A4, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | ELISA, FACS |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of MADCAM1 protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding |
| Conjucates | AF488 |
| Others Formats | Biotin/APC/PE/AF555/AF647 |
| Antibody Types Available | 3 |
| Immunogen | MADCAM1 |
| Antigen Species | Human |
| Gene ID | 8174 |
| Uniprot ID | |
| Biology Area | Drug Target |
| Molecular Weight | 150 kDa |
Stability & Storage
| Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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