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Anti-MCAM Monoclonal Antibody-AF488

Anti-MCAM Monoclonal Antibody-AF488
Anti-MCAM Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting MCAM. Anti-MCAM Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF.
Catalog No. TMAZ-0041A4

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Anti-MCAM Monoclonal Antibody-AF488

Catalog No. TMAZ-0041A4Alias S-endo 1 endothelial-associated antigen, Melanoma-associated antigen MUC18, Melanoma-associated antigen A32, Melanoma cell adhesion molecule, Cell surface glycoprotein P1H12, Cell surface glycoprotein MUC18

Anti-MCAM Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting MCAM. Anti-MCAM Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF.
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Pack SizePriceAvailabilityQuantity
25 μgInquiry12 days
50 μgInquiry12 days
100 μgInquiry12 days
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Product Introduction

Bioactivity
Description
Anti-MCAM Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting MCAM. Anti-MCAM Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF.
AliasS-endo 1 endothelial-associated antigen, Melanoma-associated antigen MUC18, Melanoma-associated antigen A32, Melanoma cell adhesion molecule, Cell surface glycoprotein P1H12, Cell surface glycoprotein MUC18
Ig Type
Rabbit monoclonal IgG
Reactivity
Human
Verified Activity
Flow cytometry analysis of MCAM overexpressed 307F cells with TMAZ-0041A4, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
Application
ELISA, FACS, IF
Recommended Dose
0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted
ConstructionThis antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of MCAM protein.
PurificationProtein A Affinity Purified
AppearanceLiquid
Formulation0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin.
Purity> 95% as determined by SDS-PAGE.
Research BackgroundPlays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as a surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration
Related Conjugates and Formulations
Conjucates
AF488
Others Formats
Biotin/APC/PE/AF555/AF647
Antibody Types Available
1
Antigen Details
Immunogen
MCAM
Antigen Species
Human
Gene ID
4162
Uniprot ID
Biology Area
Immunology Research
Chemical Properties
Molecular Weight150 kDa
Stability & Storage
Stability & StorageFor unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze.
TransportFor unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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