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Anti-MCAM Monoclonal Antibody-APC
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Catalog No. TMAZ-0041A
Alias S-endo 1 endothelial-associated antigen, Melanoma-associated antigen MUC18, Melanoma-associated antigen A32, Melanoma cell adhesion molecule, Cell surface glycoprotein P1H12, Cell surface glycoprotein MUC18
Anti-MCAM Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting MCAM. Anti-MCAM Monoclonal Antibody-APC can be used in ELISA, FACS, IF.
Anti-MCAM Monoclonal Antibody-APC
Anti-MCAM Monoclonal Antibody-APC
😃Good
Catalog No. TMAZ-0041AAlias S-endo 1 endothelial-associated antigen, Melanoma-associated antigen MUC18, Melanoma-associated antigen A32, Melanoma cell adhesion molecule, Cell surface glycoprotein P1H12, Cell surface glycoprotein MUC18
Anti-MCAM Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting MCAM. Anti-MCAM Monoclonal Antibody-APC can be used in ELISA, FACS, IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 μg | $570 | 12 days | |
| 50 μg | $945 | 12 days | |
| 100 μg | $1,415 | 12 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-MCAM Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting MCAM. Anti-MCAM Monoclonal Antibody-APC can be used in ELISA, FACS, IF. |
| Alias | S-endo 1 endothelial-associated antigen, Melanoma-associated antigen MUC18, Melanoma-associated antigen A32, Melanoma cell adhesion molecule, Cell surface glycoprotein P1H12, Cell surface glycoprotein MUC18 |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of MCAM overexpressed 307F cells with TMAZ-0041A, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | ELISA, FACS, IF |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of MCAM protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as a surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration |
| Conjucates | APC |
| Others Formats | Biotin/PE/AF488/AF555/AF647 |
| Antibody Types Available | 1 |
| Immunogen | MCAM |
| Antigen Species | Human |
| Gene ID | 4162 |
| Uniprot ID | |
| Biology Area | Immunology Research |
| Molecular Weight | 150 kDa |
Stability & Storage
| Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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