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Anti-SERPINA1 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting SERPINA1. Anti-SERPINA1 Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 μg | $570 | 12 days | |
50 μg | $945 | 12 days | |
100 μg | $1,415 | 12 days |
Description | Anti-SERPINA1 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting SERPINA1. Anti-SERPINA1 Monoclonal Antibody-AF488 can be used in ELISA, FACS, IF. |
Alias | Serpin A1, Alpha-1-antitrypsin, Alpha-1-antiproteinase, Alpha-1 protease inhibitor |
Ig Type | Rabbit monoclonal IgG |
Reactivity | Human |
Verified Activity | Flow cytometry analysis of SERPINA1 overexpressed 324F cells with TMAZ-0241A4, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
Application | ELISA, FACS, IF |
Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Subcellular Localization | Single-pass type I membrane |
Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of SERPINA1 protein. |
Purification | Protein A Affinity Purified |
Appearance | Liquid |
Formulation | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
Purity | > 95% as determined by SDS-PAGE. |
Research Background | Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin|Reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE) |
Conjucates | AF488 |
Others Formats | Biotin/APC/PE/AF555/AF647 |
Antibody Types Available | 3 |
Immunogen | SERPINA1 |
Antigen Species | Human |
Gene ID | 5265 |
Uniprot ID | |
Biology Area | Other Functions |
Molecular Weight | 150 kDa |
Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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