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Anti-TIMP1 Monoclonal Antibody-AF555
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Catalog No. TMAZ-0042A5
Alias Tissue inhibitor of metalloproteinases 1, Metalloproteinase inhibitor 1, Fibroblast collagenase inhibitor, Erythroid-potentiating activity
Anti-TIMP1 Monoclonal Antibody-AF555 is a Biotin-conjugated rabbit antibody targeting TIMP1. Anti-TIMP1 Monoclonal Antibody-AF555 can be used in ELISA, FACS, IF.
Anti-TIMP1 Monoclonal Antibody-AF555
Anti-TIMP1 Monoclonal Antibody-AF555
😃Good
Catalog No. TMAZ-0042A5Alias Tissue inhibitor of metalloproteinases 1, Metalloproteinase inhibitor 1, Fibroblast collagenase inhibitor, Erythroid-potentiating activity
Anti-TIMP1 Monoclonal Antibody-AF555 is a Biotin-conjugated rabbit antibody targeting TIMP1. Anti-TIMP1 Monoclonal Antibody-AF555 can be used in ELISA, FACS, IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 μg | $570 | 12 days | |
| 50 μg | $945 | 12 days | |
| 100 μg | $1,415 | 12 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-TIMP1 Monoclonal Antibody-AF555 is a Biotin-conjugated rabbit antibody targeting TIMP1. Anti-TIMP1 Monoclonal Antibody-AF555 can be used in ELISA, FACS, IF. |
| Alias | Tissue inhibitor of metalloproteinases 1, Metalloproteinase inhibitor 1, Fibroblast collagenase inhibitor, Erythroid-potentiating activity |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of TIMP1 overexpressed 303F cells with TMAZ-0042A5, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | ELISA, FACS, IF |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of TIMP1 protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors |
| Conjucates | AF555 |
| Others Formats | Biotin/APC/PE/AF488/AF647 |
| Antibody Types Available | 3 |
| Immunogen | TIMP1 |
| Antigen Species | Human |
| Gene ID | 7076 |
| Uniprot ID | |
| Biology Area | Immunology Research |
| Molecular Weight | 150 kDa |
Stability & Storage
| Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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