Lipid Metabolism Compound Library

Catalog No. L2510

Library Compound List Excel SDF

Lipids are fatty acids and their derivatives, and substances related biosynthetically or functionally to these compounds. Lipids are commonly subdivided into four main groups: fatty acids (saturated and unsaturated), glycerides (glycerol-containing lipids), nonglyceride lipids (sphingolipids, steroids, waxes), and complex lipids (lipoproteins). Like the other large biological molecules, lipids perform many different functions in a cell. Lipids are critical for cell structure, function, and energy, as well as organs and body insulation and protection. Lipid metabolism is the synthesis and degradation of lipids in cells, involving the breakdown or storage of fats for energy and the synthesis of structural and functional lipids, such as those involved in the construction of cell membranes. Lipids metabolites are extremely essential for a wide range of cellular communication and metabolism.

Numerous studies have shown that lipid metabolism plays an important role in the pathogenesis of a wide range of chronic diseases such as cardiovascular disease, aging, and cancer, etc. Lipid metabolism has now been accepted as a major metabolic pathway that is involved in many aspects of cancer cell biology. Discovering novel mechanisms of the lipid role in diseases and new ways to exploit these mechanisms for the optimal drug design would be beneficial for the prevention and treatment of these diseases.

TargetMol’s Lipid Metabolism Compound Library collects 496 compounds acting on key targets related to lipid metabolism, such as Acetyl-CoA Carboxylase、Acyltransferase、cholesteryl ester transfer protein (CETP)、FAAH、Fatty Acid Synthase (FASN)、HMG-CoA Reductase (HMGCR), etc. It is a powerful tool that can be used in lipid metabolism related drug development and mechanism studies.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)

Request for Quote

If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com

Request Library

Product Description

A unique collection of 496 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).
Covers several important targets, key components in lipid metabolism pathway, such as Acetyl-CoA Carboxylase、Acyltransferase、cholesteryl ester transfer protein (CETP)、FAAH、Fatty Acid Synthase (FASN)、HMG-CoA Reductase (HMGCR), etc.
Detailed compound information with structure, target, and biological activity description.
NMR and HPLC validated to ensure high purity and quality.

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files

Publications Cited TargetMol Libraries

1. Cell Death & Disease. 2022, 13(9): 1-15. 2. Cell Stem Cell. 2022 Apr 29(4) 545–558. 3. Science Bulletin. 2022. 4. Science Translational Medicine. 2022, 14(656): eabn3231. 5. Science Advances. 2023, 9(9): eade3760. 6. Nature. 2020, 582: 289-293. 7. Nature Biotechnology. 2021, 39(11): 1444-1452. 8. Nature Communications. 2022, 13(1): 1-15.. 9. Nature Communications. 2023, 14(1): 1020..

10. Nature Communications. 2023, 14(1): 2756.. 11. Blood. 2021, 137(11): 1478-1490. 12. Nucleic Acids Research. 2021. 13. Nature Communications. 2023, 14(1): 7574. 14. Advanced Science. 2020, 7(16): 2000925. 15. Angewandte Chemie. 2021. 16. Acta Pharmaceutica Sinica B. 2022. 17. Protein & Cell. 2021, 12(11): 877-888. 18. Bone Research. 2023, 11(1): 54. 19. Pharmacology & Therapeutics. (2021): 107930. 20. Nature Communications. 2021, 12(1): 1-12. 21. Journal of Cell Biology. 2022, 221(5): e202112024.

See More... Hide

Library Composition

PPAR (99)

Autophagy (96)

Apoptosis (63)

Phospholipase (38)

Lipoxygenase (37)

Endogenous Metabolite (37)

AMPK (36)

COX (35)

Antibacterial (27)

FAAH (26)

P450 (23)

Fatty Acid Synthase (23)

Retinoid Receptor (20)

Ferroptosis (20)

HMG-CoA Reductase (20)

ROS (20)

FXR (20)

Phosphatase (19)

Reactive Oxygen Species (17)

Dehydrogenase (16)

NF-κB (14)

Acyltransferase (14)

Lipase (12)

Antifungal (11)

Acetyl-CoA Carboxylase (11)

ROR (10)

Mitophagy (10)

Liver X Receptor (10)

Mitochondrial Metabolism (9)

Stearoyl-CoA Desaturase (SCD) (8)

Isocitrate Dehydrogenase (IDH) (8)

PARP (8)

Parasite (8)

Influenza Virus (7)

Potassium Channel (7)

ATP Citrate Lyase (7)

PKM (7)

Antibiotic (7)

Akt (7)

Wnt/beta-catenin (7)

NADPH (7)

Prostaglandin Receptor (6)

NADPH-oxidase (5)

Reductase (5)

Phosphorylase (5)

Sirtuin (5)

TRP/TRPV Channel (5)

Estrogen/progestogen Receptor (5)

Epoxide Hydrolase (5)

CETP (5)

Calcium Channel (5)

Cannabinoid Receptor (5)

AChR (5)

Lipid (4)

Virus Protease (4)

Leukotriene Receptor (4)

HSV (4)

NPC1L1 (3)

Tyrosinase (3)

VEGFR (3)

MMP (3)

TNF (3)

transporter (3)

MAGL (3)

PDE (3)

Chloride channel (3)

Transferase (3)

Proton pump (3)

Glutathione Peroxidase (3)

SIK (3)

Estrogen Receptor/ERR (3)

DNA/RNA Synthesis (3)

SARS-CoV (3)

JNK (2)

Caspase (2)

PGC-1α (2)

GABA Receptor (2)

p53 (2)

Anti-infection (2)

Nrf2 (2)

Glucocorticoid Receptor (2)

BCL (2)

PI3K (2)

GPR (2)

GPCR19 (2)

RSV (2)

TGF-beta/Smad (2)

LTR (2)

IL Receptor (2)

STAT (2)

HIF/HIF Prolyl-Hydroxylase (2)

c-Met/HGFR (2)

Interleukin (2)

SGLT (1)

RAAS (1)

PKA (1)

Thrombin (1)

UGT (1)

PKC (1)

Proteasome (1)

Tyrosine Kinases (1)

S1P Receptor (1)

Serine Protease (1)

TAM Receptor (1)

ribosome (1)

Trk receptor (1)

RAR/RXR (1)

ROS Kinase (1)

Ras (1)

5-HT Receptor (1)

PERK (1)

c-Kit (1)

FABP (1)

ERK (1)

EGFR (1)

Drug Metabolite (1)

DNA (1)

Cysteine Protease (1)

c-RET (1)

CDK (1)

FLT (1)

CaMK (1)

Aromatase (1)

Antioxidant (1)

Androgen Receptor (1)

Adrenergic Receptor (1)

Adenylyl cyclase (1)

Adenosine Receptor (1)

AChE (1)

FLAP (1)

Gamma-secretase (1)

PAK (1)

IAP (1)

Opioid Receptor (1)

Monocarboxylate transporter (1)

Melatonin Receptor (1)

LDL (1)

IκB/IKK (1)

ABC (1)

Immunology/Inflammation related (1)

iGluR (1)

Hydroxylase (1)

Glucosidase (1)

HIV Protease (1)

Histone Demethylase (1)

Histamine Receptor (1)

HIF (1)

HCV Protease (1)

HBV (1)

GST (1)

GSK-3 (1)

YAP (1)

Library Information Sample

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty