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TargetMol | Compound Library

MAPK Inhibitor Library

Catalog No. L1400

Mitogen-activated protein kinases (MAPKs) are a highly conserved family of serine/threonine protein kinases involved in a variety of fundamental cellular processes such as proliferation, differentiation, motility, stress response, apoptosis, and survival. A broad range of extracellular stimuli including mitogens, cytokines, growth factors, and environmental stressors stimulate the activation of one or more MAPKK kinases (MAPKKKs) via receptor-dependent and -independent mechanisms. MAPKKKs then phosphorylate and activate a downstream MAPK kinase (MAPKK), which in turn phosphorylates and activates MAPKs. The MAPK Inhibitor Library by TargetMol, containing 365 compounds targeting MAPK signaling, can be used for research in MAPK signaling, and drug screening for related diseases.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1400

MAPK Inhibitor Library
sizeIn stock
  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
  • Targets include ERK, JNK, MEK, p38, MAPK, Raf, RSK, MNK, etc;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
Inquiry & Custom

Library Customization | TargetMol Library Composition

Apoptosis
ERK
p38 MAPK
Autophagy
Raf
Ras
MEK
JNK
NF-κB
MAPK
S6 Kinase
CDK
Akt
Src
VEGFR
Rho
Caspase
Aurora Kinase
Endogenous Metabolite
PDGFR
c-Kit
Ferroptosis
mTOR
Casein Kinase
PI3K
GSK-3
PKA
Parasite
ROCK
TGF-beta/Smad
c-RET
TNF
MLK
Antifungal
PKC
Bcr-Abl
BCL
COX
Antibacterial
MNK
STAT
AMPK
FLT
PERK
TOPK
PARP
MMP
DNA/RNA Synthesis
Trk receptor
ASK
P450
SGK
Serine Protease
Reactive Oxygen Species
JAK
IGF-1R
EGFR
LRRK2
FGFR
Transferase
c-Met/HGFR
GTPase
Mitophagy
Aryl Hydrocarbon Receptor
ROS
DNA Alkylation
AChE
P-gp
Antiviral
Influenza Virus
Beta Amyloid
c-Fms
KLF
Syk
Sodium Channel
FAK
NO Synthase
Proton pump
HCV Protease
Integrin
Estrogen/progestogen Receptor
Dehydrogenase
Antioxidant
Adenosine Receptor
BACE
Histamine Receptor
Tie-2
Glutathione Peroxidase
Virus Protease
c-Myc
HBV
Tyrosine Kinases
FXR
Calcium Channel
Adrenergic Receptor
CSF-1R
Topoisomerase
RIP kinase
Drug Metabolite
Glucosidase
Antifection
IL Receptor
Chk
ACK
cAMP
Epigenetic Reader Domain
DNA
Interleukin
Beta-Secretase
PGE Synthase
TLR
Ephrin Receptor
transporter
Nrf2
PAI-1
ALK
MELK
IκB/IKK
GPX
Aromatase
PDK
5-HT Receptor
Hydroxylase
Potassium Channel
AChR
BMI-1
NADPH-oxidase
IRAK
Tyrosinase
Antibiotic
HIF/HIF Prolyl-Hydroxylase
AhR
PD-1/PD-L1
Kinesin

Keywords