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TargetMol | Compound Library

MAPK Inhibitor Library

Catalog No. L1400

Mitogen-activated protein kinases (MAPKs) are a highly conserved family of serine/threonine protein kinases involved in a variety of fundamental cellular processes such as proliferation, differentiation, motility, stress response, apoptosis, and survival. A broad range of extracellular stimuli including mitogens, cytokines, growth factors, and environmental stressors stimulate the activation of one or more MAPKK kinases (MAPKKKs) via receptor-dependent and -independent mechanisms. MAPKKKs then phosphorylate and activate a downstream MAPK kinase (MAPKK), which in turn phosphorylates and activates MAPKs. The MAPK Inhibitor Library by TargetMol, containing 500 compounds targeting MAPK signaling, can be used for research in MAPK signaling, and drug screening for related diseases.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1400

MAPK Inhibitor Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 500 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
  • Targets include ERK, JNK, MEK, p38, MAPK, Raf, RSK, MNK, etc;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

p38 MAPK
ERK
Apoptosis
Raf
Autophagy
MAPK
Ras
JNK
Kras
MEK
NF-κB
S6 Kinase
CDK
Akt
VEGFR
Src
TNF
Rho
MNK
PI3K
PDGFR
mTOR
c-Kit
GSK-3
PKA
Caspase
Aurora Kinase
Casein Kinase
Endogenous Metabolite
FLT
MLK
BCL
Ferroptosis
Parasite
PKC
JAK
Antibacterial
STAT
ROCK
IGF-1R
COX
TGF-beta/Smad
c-RET
Bcr-Abl
IL Receptor
MMP
EGFR
ASK
FGFR
Antifungal
TOPK
PARP
Reactive Oxygen Species
DNA/RNA Synthesis
Antiviral
AMPK
P450
SGK
FAK
Tyrosine Kinases
Serine Protease
BTK
AChE
TLR
Trk receptor
ALK
Influenza Virus
c-Fms
KLF
Syk
Antibiotic
NO Synthase
PROTACs
Transferase
Histone Methyltransferase
HCV Protease
Dehydrogenase
Antioxidant
GTPase
Mitophagy
Virus Protease
PPAR
Pim
PYK2
Calcium Channel
Aryl Hydrocarbon Receptor
Drug Metabolite
Mitochondrial Metabolism
Antifection
ROS
Chk
ACK
Epigenetic Reader Domain
P-gp
Nrf2
GPR
PDK
Potassium Channel
AChR
IRAK
HER
Apelin receptor
ATPase
MyD88
Estrogen/progestogen Receptor
c-Met/HGFR
BACE
DYRK
Histamine Receptor
Tie-2
Glutathione Peroxidase
c-Myc
HBV
Wnt/beta-catenin
TRP/TRPV Channel
Adrenergic Receptor
CSF-1R
iGluR
Topoisomerase
RIP kinase
PDE
LDL
NMDAR
Glucosidase
DNA Alkylation
PTEN
GluR
cAMP
Interleukin
Beta-Secretase
PGE Synthase
HSP
Prostaglandin Receptor
LRRK2
Ephrin Receptor
transporter
PAI-1
MELK
IκB/IKK
Hippo pathway
Beta Amyloid
GPX
Aromatase
5-HT Receptor
Hydroxylase
RXFP receptor
DAPK
NADPH-oxidase
BMI-1
Sodium Channel
Tyrosinase
Protease-activated Receptor
HIF/HIF Prolyl-Hydroxylase
AhR
p53
PD-1/PD-L1
Kinesin