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Methylation Compound Library

Catalog No. L3510
  Library Compound List   Excel SDF

Methylation is an important way of protein and nucleic acid modification that regulates gene expression and is closely related to many diseases such as cancer, aging, and Alzheimer's disease. It is an important field of study in epigenetics. The most common methylation modifications are DNA methylation and histone methylation

DNA methylation, the addition of methyl groups to DNA, was one of the first methylation modifications discovered. The modification occurs specifically at the CpG site, where cytosine is attached to guanylate via phosphate. Numerous studies have shown that DNA methylation can cause changes in chromatin structure, DNA conformation, DNA stability and the way DNA interacts with proteins, thereby controlling gene expression.

Histone methylation refers to the methylation that occurs at the N-terminal arginine Arg(R) or lysine Lys(K) residues of H3 and H4 histones and is mediated and catalyzed by histone methyltransferases. Histone methylation mainly causes heterochromatin formation, gene imprinting, X chromosome inactivation and transcriptional regulation.

TargetMol Methylation Compound Library is a collection of 131 methylation-related compounds that can be used for research in epigenetics, differentiation, aging, cancer, and more.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
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Product Description

  • 125 methylation-related compounds that can be used for high-throughput and high-content screening.
  • Targets include DNA Methyltransferase, Histone Methyltransferase, etc.
  • Can be used for studies on epigenetics, differentiation, aging, cancer, etc.
  • Detailed instructions, compound structure, target information, activity description, etc.
  • NMR and HPLC analytical techniques to ensure high product purity and quality.
  • All compounds are available in stock.

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L3510)

Library Composition

Histone Methyltransferase (72)
Histone Demethylase (26)
DNA Methyltransferase (13)
JAK (3)
Sodium Channel (3)
Histamine Receptor (2)
Epigenetic Reader Domain (2)
MAO (2)
AChR (2)
5-HT Receptor (2)
DNA Alkylation (1)
Calcium Channel (1)
Apoptosis (1)
Antifungal (1)
Antifolate (1)
Androgen Receptor (1)
DUB (1)
Tyrosine Kinases (1)
Ras (1)
PGE Synthase (1)
Endogenous Metabolite (1)
NMDAR (1)
Mitochondrial Metabolism (1)
HDAC (1)
Glucocorticoid Receptor (1)
Estrogen/progestogen Receptor (1)
P450 (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE