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Potassium Channel Blocker Library

Catalog No. L7300
  Library Compound List   Excel SDF

Potassium channels are the most widely distributed type of ion channel and are found in virtually all living organisms. They form potassium-selective pores that span cell membranes. Furthermore, potassium channels are found in most cell types and control a wide variety of cell functions, such as regulation of cellular excitability, neurotransmitter release, protecting cardiac myocytes, and anti-arrhythmia function, and are involved in learning and memory process, and temperature control. Potassium channel blockers is a class of drugs that act by inhibition of potassium efflux through cell membranes, including inorganic ions (Cs, Ba) and organic molecules (TEA, 4-AP), toxins (scorpion venoms, snake venoms, and bee venoms), and potassium channel blockers in clinical use.

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Product Description

  • A unique collection of 160 potassium channel blockers and agonists for high throughput and high content screening;
  • Targeting different subtypes of potassium channels, such as Kir1.1, Kir3.x, Kir6.x and Kv7.1, etc.
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, some of which are FDA approved;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

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Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
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Library Composition

Potassium Channel (114)
Sodium Channel (13)
EGFR (9)
Adrenergic Receptor (8)
5-HT Receptor (7)
Dopamine Receptor (5)
Calcium Channel (5)
HER (5)
ATPase (5)
AChR (4)
Carbonic Anhydrase (4)
PPAR (3)
NMDAR (3)
COX (3)
NADPH (3)
MRP (3)
ABC (3)
GPR (2)
LDL (2)
Integrin (2)
TRP/TRPV Channel (2)
VEGFR (2)
Chloride channel (2)
GABA Receptor (2)
Gap Junction Protein (1)
AMPK (1)
Topoisomerase (1)
TNF (1)
Thrombin (1)
Antifection (1)
Autophagy (1)
BCRP (1)
PKC (1)
PAI-1 (1)
P450 (1)
CaMK (1)
NOS (1)
NOD (1)
NF-κB (1)
GluR (1)
CXCR (1)
mTOR (1)
DNA (1)
DNA gyrase (1)
JNK (1)
IκB/IKK (1)
DNA/RNA Synthesis (1)
IL Receptor (1)
HSP (1)
HMG-CoA Reductase (1)
Histamine Receptor (1)
ERK (1)
Estrogen/progestogen Receptor (1)
HIF (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE