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(R)-Praziquantel-d11

Catalog No. T12638 CAS 1399880-38-6

Synonyms: (R)-Praziquantel D11

(R)-Praziquantel D11 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel is the active enantiomer of Praziquantel, is a partial the human 5-HT2B receptor agonist

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(R)-Praziquantel-d11, CAS 1399880-38-6

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	(R)-Praziquantel D11 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel is the active enantiomer of Praziquantel, is a partial the human 5-HT2B receptor agonist
In vitro	(R)-Praziquantel modulation of serotoninergic signaling occurs over a concentration range sufficient to regulate vascular tone of the mesenteric blood vessels where the adult parasites reside within their host. The important anthelmintic is supported by a broad, cross species polypharmacology with (R)-Praziquantel modulating signaling events in both host and parasite.

Synonyms	(R)-Praziquantel D11
Molecular Weight	323.47
Formula	C19H24N2O2
CAS No.	1399880-38-6

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Chan JD, et al. The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand. Nat Commun. 2017 Dec 5;8(1):1910.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

(R)-Praziquantel-d11 1399880-38-6 GPCR/G Protein Neuroscience 5-HT Receptor (R)-Praziquantel D11 (R) Praziquantel d11 (R)Praziquanteld11 (R)-Praziquantel-d-11 Inhibitor inhibitor inhibit

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