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Anti-IFNL3 Monoclonal Antibody-AF488
Anti-IFNL3 Monoclonal Antibody-AF488
Anti-IFNL3 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting IFNL3. Anti-IFNL3 Monoclonal Antibody-AF488 can be used in ELISA, FACS.
Catalog No. TMAZ-0008A4
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Anti-IFNL3 Monoclonal Antibody-AF488
Catalog No. TMAZ-0008A4Alias Interleukin-28C, Interleukin-28B, Interferon lambda-3, Cytokine Zcyto22
Anti-IFNL3 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting IFNL3. Anti-IFNL3 Monoclonal Antibody-AF488 can be used in ELISA, FACS.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 μg | $570 | 12 days | |
| 50 μg | $945 | 12 days | |
| 100 μg | $1,415 | 12 days |
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Antigen Details
Chemical Properties
| Description | Anti-IFNL3 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting IFNL3. Anti-IFNL3 Monoclonal Antibody-AF488 can be used in ELISA, FACS. |
| Alias | Interleukin-28C, Interleukin-28B, Interferon lambda-3, Cytokine Zcyto22 |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of IFNL3 overexpressed 411F cells with TMAZ-0008A4, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | ELISA, FACS |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of IFNL3 protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression |
| Conjucates | AF488 |
| Others Formats | Biotin/APC/PE/AF555/AF647 |
| Antibody Types Available | 1 |
| Immunogen | IFNL3 |
| Antigen Species | Human |
| Gene ID | 282617 |
| Uniprot ID | |
| Biology Area | Immunology Research |
| Molecular Weight | 150 kDa |
Stability & Storage
| Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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