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Anti-MUC1 Monoclonal Antibody-AF555 is a Biotin-conjugated rabbit antibody targeting MUC1. Anti-MUC1 Monoclonal Antibody-AF555 can be used in ELISA, FACS.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 μg | $570 | 12 days | |
50 μg | $945 | 12 days | |
100 μg | $1,415 | 12 days |
Description | Anti-MUC1 Monoclonal Antibody-AF555 is a Biotin-conjugated rabbit antibody targeting MUC1. Anti-MUC1 Monoclonal Antibody-AF555 can be used in ELISA, FACS. |
Alias | Tumor-associated mucin, Tumor-associated epithelial membrane antigen, Polymorphic epithelial mucin, PEMT, Peanut-reactive urinary mucin, Mucin-1, Krebs von den Lungen-6, H23AG, Episialin, Carcinoma-associated mucin, Cancer antigen 15-3, Breast carcinoma-associated antigen DF3 |
Ig Type | Rabbit monoclonal IgG |
Reactivity | Human |
Verified Activity | Flow cytometry analysis of MUC1 overexpressed 395F cells with TMAZ-0113A5, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
Application | ELISA, FACS |
Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Subcellular Localization | Secreted |
Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of MUC1 protein. |
Purification | Protein A Affinity Purified |
Appearance | Liquid |
Formulation | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
Purity | > 95% as determined by SDS-PAGE. |
Research Background | The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack|The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity |
Conjucates | AF555 |
Others Formats | Biotin/APC/PE/AF488/AF647 |
Antibody Types Available | 1 |
Immunogen | MUC1 |
Antigen Species | Human |
Gene ID | 4582 |
Uniprot ID | |
Biology Area | Cancer Research |
Molecular Weight | 150 kDa |
Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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