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Anti-NECTIN2 Monoclonal Antibody-AF555

Catalog No. TMAZ-0230A5
Alias Poliovirus receptor-related protein 2, Nectin-2, Nectin cell adhesion molecule 2, Herpes virus entry mediator B

Anti-NECTIN2 Monoclonal Antibody-AF555 is a Biotin-conjugated rabbit antibody targeting NECTIN2. Anti-NECTIN2 Monoclonal Antibody-AF555 can be used in ELISA, FACS.

Anti-NECTIN2 Monoclonal Antibody-AF555

Anti-NECTIN2 Monoclonal Antibody-AF555

Catalog No. TMAZ-0230A5Alias Poliovirus receptor-related protein 2, Nectin-2, Nectin cell adhesion molecule 2, Herpes virus entry mediator B
Anti-NECTIN2 Monoclonal Antibody-AF555 is a Biotin-conjugated rabbit antibody targeting NECTIN2. Anti-NECTIN2 Monoclonal Antibody-AF555 can be used in ELISA, FACS.
Pack SizePriceAvailabilityQuantity
25 μg$39512 days
50 μg$65512 days
100 μg$98512 days
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Product Introduction

Bioactivity
Description
Anti-NECTIN2 Monoclonal Antibody-AF555 is a Biotin-conjugated rabbit antibody targeting NECTIN2. Anti-NECTIN2 Monoclonal Antibody-AF555 can be used in ELISA, FACS.
AliasPoliovirus receptor-related protein 2, Nectin-2, Nectin cell adhesion molecule 2, Herpes virus entry mediator B
Ig Type
Rabbit monoclonal IgG
Reactivity
Human
Verified Activity
Flow cytometry analysis of NECTIN2 overexpressed 439F cells with TMAZ-0230A5, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
Application
ELISA, FACS
Recommended Dose
0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted
ConstructionThis antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of NECTIN2 protein.
PurificationProtein A Affinity Purified
AppearanceLiquid
Formulation0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin.
Purity> 95% as determined by SDS-PAGE.
Research BackgroundModulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive (PubMed: 26755705). Probable cell adhesion protein (PubMed: 9657005)|(Microbial infection) Acts as a receptor for herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV)
Related Conjugates and Formulations
Conjucates
AF555
Others Formats
Biotin/APC/PE/AF488/AF647
Antibody Types Available
1
Antigen Details
Immunogen
NECTIN2
Antigen Species
Human
Gene ID
5819
Uniprot ID
Biology Area
Other Functions
Chemical Properties
Molecular Weight150 kDa
Stability & Storage
Stability & StorageFor unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze.
TransportFor unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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