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Manoalide

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Catalog No. T68752Cas No. 75088-80-1

Manoalide, a sesterterpenoid compound, serves as a potent inhibitor of Phospholipase A2 (PLA2) and Phospholipase C (PLC). It exhibits anti-inflammatory and antibacterial properties.

Manoalide

Manoalide

😃Good
Catalog No. T68752Cas No. 75088-80-1
Manoalide, a sesterterpenoid compound, serves as a potent inhibitor of Phospholipase A2 (PLA2) and Phospholipase C (PLC). It exhibits anti-inflammatory and antibacterial properties.
Pack SizePriceAvailabilityQuantity
25 mgInquiry8-10 weeks
50 mgInquiry8-10 weeks
100 mgInquiry8-10 weeks
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Product Introduction

Bioactivity
Description
Manoalide, a sesterterpenoid compound, serves as a potent inhibitor of Phospholipase A2 (PLA2) and Phospholipase C (PLC). It exhibits anti-inflammatory and antibacterial properties.
In vitro
FV-100 (1 h) produces a different distribution in HeLa cells.[1]
In vivo
FV-100 (50-500 mg/kg ; oral) does not result in biologically related respiratory changes or significant neuropharmacological effects in rats.[2]
Chemical Properties
Molecular Weight416.55
FormulaC25H36O5
Cas No.75088-80-1
Storage & Solubility Information
StorageShipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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