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Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 μg | $75 | 35 days | |
1 mg | $140 | 35 days | |
5 mg | $563 | 35 days | |
10 mg | $980 | 35 days |
Description | SPD304 is a selective TNF-α inhibitor and blocks the interaction of TNF and its receptor. SPD304 has an IC50 of 22 µM for inhibiting in vitro TNF receptor 1 binding to TNF-α. |
In vitro | SPD304 (2 μM) obviously rescues the survivability of aHSCs, reduces the production of lipid hydroxides, and increased intracellular GSH. The co-treatment of GA (75 μM) and SPD304 (2 μM), down-regulate TRADD almost 2-fold and p−RIP3 1.4−fold compared to GA alone and promotes caspase 8 activation [4]. |
Molecular Weight | 547.61 |
Formula | C32H32F3N3O2 |
Cas No. | 869998-49-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 24 mg/mL (43.83 mM) H2O: 18 mg/mL (32.87 mM) | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
DMSO/H2O
DMSO
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