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BTN3A3 Protein, Human, Recombinant (His)

Catalog No. TMPY-03967

BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1.

BTN3A3 Protein, Human, Recombinant (His)

BTN3A3 Protein, Human, Recombinant (His)

Catalog No. TMPY-03967
BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1.
Pack SizePriceAvailabilityQuantity
100 μg$386In Stock
200 μg$6827-10 days
500 μg$1,4407-10 days
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Product Information

Biological Activity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1.
Species
Human
Expression System
HEK293 Cells
TagC-His
Accession NumberO00478-1
Synonyms
butyrophilin subfamily 3 member A3,BTN3A3,BTN3.3,BTF3
Construction
A DNA sequence encoding the human BTN3A3(O00478-1) (Met1-Trp248) was expressed with a C-terminal polyhistidine tag. Predicted N terminal: Gln 30
Protein Purity
> 95 % as determined by SDS-PAGE
BTN3A3 Protein, Human, Recombinant (His)
Molecular Weight25 kDa (predicted); 32 kDa (reducing conditions)
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution
A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice.
Research Background
The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. The butyrophilin 3 (BTN3) receptors are implicated in the T lymphocytes regulation and present a wide plasticity in mammals. A thorough phylogenetic analysis reveals a concerted evolution of BTN3 characterized by a strong and recurrent homogenization of the region encoding the signal peptide and the immunoglobulin variable (IgV) domain in Hominoids, where the sequences of BTN3A1 or BTN3A3 are replaced by BTN3A2 sequence.

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Please read the User Guide of Recombinant Proteins for more specific information.

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