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GUCY2C Protein, Cynomolgus, Recombinant (aa 24-430, His)
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GUCY2C Protein, Cynomolgus, Recombinant (aa 24-430, His)
Catalog No. TMPK-01279
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Cynomolgus, Recombinant (aa 24-430, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 47.2 kDa and the accession number is XP_005570270.1.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μg | $487 | 7-10 days | |
| 500 μg | $1,950 | 7-10 days | |
| 1 mg | $3,250 | 7-10 days |
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Biological Description
| Biological Information | Immobilized Cynomolgus GUCY2C, His Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-GUCY2C Antibody, hFc Tag with the EC50 of 0.68μg/ml determined by ELISA. |
| Description | Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Cynomolgus, Recombinant (aa 24-430, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 47.2 kDa and the accession number is XP_005570270.1. |
| Species | Cynomolgus |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | XP_005570270.1 |
| Synonyms | GUC2CEC 4.6.1.2,GCC,Guanylyl cyclase C,STA receptor,MUCIL,GUC2C,EC 4.6.1,STAR,DIAR6,GUCY2C,GC-C |
| Construction | Ser24-Gln430 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Molecular Weight | 47.2 kDa (predicted). Due to glycosylation, the protein migrates to 60-75 kDa based on Tris-Bis PAGE result. |
| Endotoxin | < 1 EU/μg by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, Lyophilized powders are shipping with blue ice. |
| Research Background | Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. |
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