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Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant is expressed in yeast. The predicted molecular weight is 19.5 kDa and the accession number is B6CK11.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | $539 | 7-10 days |
Biological Activity | Measured in antiviral assay using WISH cells infected with vesicμLar stomatitis virus. The ED50 for this effect is typically 1.8-7.4 pg/mL. |
Description | Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant is expressed in yeast. The predicted molecular weight is 19.5 kDa and the accession number is B6CK11. |
Species | Rhesus |
Expression System | P. pastoris (Yeast) |
Tag | Tag Free |
Accession Number | B6CK11 |
Synonyms | interferon, α2,interferon, alpha 2,Interferon α2/IFNA2 |
Construction | A DNA sequence encoding the rhesus IFNA2 (NP_001129266.1) (Cys24-Glu188) was expressed. Predicted N terminal: Cys 24 |
Protein Purity | > 90 % as determined by SDS-PAGE |
Molecular Weight | 19.5 kDa (predicted) |
Endotoxin | Please contact us for more information. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping | In general, Lyophilized powders are shipping with blue ice. |
Research Background | IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interferons (IFNs) are well-known cytokines that exert antiviral activity, antitumor activity, and immunomodulatory effects. Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. Among the IFN-α genes, a total of 28 different sequence variants have been described. The three principal subtypes of IFNα-2 are designated α-2a, α-2b, and α-2c. IFNα-2b is being the predominant allele while IFNα-2a is less predominant and IFNα-2c only a minor allelic variant. |
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