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NXPH1 Protein, Mouse, Recombinant (His)

Catalog No. TMPY-03126

NXPH1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.1 kDa and the accession number is Q61200.

NXPH1 Protein, Mouse, Recombinant (His)

NXPH1 Protein, Mouse, Recombinant (His)

Catalog No. TMPY-03126
NXPH1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.1 kDa and the accession number is Q61200.
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100 μg570 €7-10 days
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Product Information

Biological Activity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
NXPH1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.1 kDa and the accession number is Q61200.
Species
Mouse
Expression System
HEK293 Cells
TagC-His
Accession NumberQ61200
Synonyms
neurexophilin 1,C130005L03Rik
Construction
A DNA sequence encoding the mouse NXPH1 (Q61200) (Ala22-Gly271) was expressed with a C-terminal polyhistidine tag. Predicted N terminal: Ala 22
Protein Purity
> 85 % as determined by SDS-PAGE
Molecular Weight30.1 kDa (predicted); 46-48 kDa (reducing condition, due to glycosylation)
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution
A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice.
Research Background
Neurexophilin-1 or NXPH1 is a secreted glycoprotein, which belongs to the Neurexophilin family. The Neurexophilin family contains at least four genes and resembles a neuropeptide, suggesting a function as an endogenous ligand for alpha-neurexins. The mammalian brains contain four genes for neurexophilins the products of which share a common structure composed of five domains: an N-terminal signal peptide, a variable N-terminal domain, a highly conserved central domain that is N-glycosylated, a short linker region, and a conserved C-terminal domain that is cysteine-rich. Neurexophilin-1 constitutes a secreted cysteine-rich glycoprotein, forms a very tight complex with alpha neurexins, a group of proteins that promote adhesion between dendrites and axons. Neurexophilins 1 and 3 but not 4 (neurexophilin 2 is not expressed in rodents) bind to a single individual LNS domain, the second overall LNS domain in all three alpha-neurexins.

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