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PNLIPRP1 Protein, Human, Recombinant (His)

Catalog No. TMPY-03808

PNLIPRP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.4 kDa and the accession number is AAH25784.1.

PNLIPRP1 Protein, Human, Recombinant (His)

PNLIPRP1 Protein, Human, Recombinant (His)

Catalog No. TMPY-03808
PNLIPRP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.4 kDa and the accession number is AAH25784.1.
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100 μg$7007-10 days
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Product Information

Biological Activity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
PNLIPRP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.4 kDa and the accession number is AAH25784.1.
Species
Human
Expression System
HEK293 Cells
TagC-His
Accession NumberAAH25784.1
Synonyms
PLRP1,pancreatic lipase-related protein 1
Construction
A DNA sequence encoding the human PNLIPRP1 (AAH25784.1) (Met1-Cys467) was expressed with a C-terminal polyhistidine tag. Predicted N terminal: Lys 18
Protein Purity
> 90 % as determined by SDS-PAGE
Molecular Weight51.4 kDa (predicted); 44-48 kDa (reducing conditions)
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution
A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice.
Research Background
PNLIPRP1, also known as PLRP1, belongs to the AB hydrolase superfamily, Lipase family. PNLIPRP1 is structurally similar to PLRP2. However, these two proteins display different functional properties. PNLIPRP1 may function as an inhibitor of dietary triglyceride digestion. It lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters. PLRP2 hydrolyses milk fat with lower catalytic efficiency than that of PL. PLRP2 activity, higher on homogenized than on native milk fat, is differently influenced by fatty acids and colipase depending on a proteolytic cleavage in the lid domain.

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Keywords