SG3/Secretogranin 3 Protein, Human, Recombinant (aa 20-468, His)

Catalog No. TMPK-01122

Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regulation. Unlike many other known angiogenic factors, the pro-angiogenic actions of Scg3 are restricted to pathological conditions. Among thousands of quantified endothelial ligands, Scg3 has the highest binding activity ratio to diabetic vs. SG3/Secretogranin 3 Protein, Human, Recombinant (aa 20-468, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 52.1 kDa and the accession number is Q8WXD2-1.

SG3/Secretogranin 3 Protein, Human, Recombinant (aa 20-468, His)

Catalog No. TMPK-01122

Pack Size	Price	Availability
100 μg	$418	7-10 days
500 μg	$1,670	7-10 days
1 mg	$2,800	7-10 days

Bulk & Custom

Add to Cart

Questions

Resource Download

User Guide of Recombinant Proteins

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Information

Biological Activity	Immobilized Human SG3, His Tag at 0.2μg/ml (100μl/Well) on the plate. Dose response curve for Anti-SG3 Antibody, hFc Tag with the EC50 of 20.6ng/ml determined by ELISA.
Description	Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regulation. Unlike many other known angiogenic factors, the pro-angiogenic actions of Scg3 are restricted to pathological conditions. Among thousands of quantified endothelial ligands, Scg3 has the highest binding activity ratio to diabetic vs. SG3/Secretogranin 3 Protein, Human, Recombinant (aa 20-468, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 52.1 kDa and the accession number is Q8WXD2-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	Q8WXD2-1
Synonyms	UNQ2502/PRO5990,SGIII,Secretogranin-3,Secretogranin III,SCG3
Construction	Phe20-Leu468
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	52.1 kDa (predicted). Due to glycosylation, the protein migrates to 55-68 kDa based on Tris-Bis PAGE result.
Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regulation. Unlike many other known angiogenic factors, the pro-angiogenic actions of Scg3 are restricted to pathological conditions. Among thousands of quantified endothelial ligands, Scg3 has the highest binding activity ratio to diabetic vs.