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Signaling Pathway Download


Product Name


Diseases and Conditions

T0085 Entecavir hydrate
Entecavir, a new deoxyguanine nucleoside analogue, is a selective inhibitor of the replica... Other
T6980 Scriptaid
Scriptaid is an inhibitor of HDAC. It shows a greater effect on acetylated H4 than H3. Others
T3352 XL413
XL-413 is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor wit... Cancer
T3661 ACY-241
ACY-241, also known as Citarinostat, is a potent, selective and orally available histone d... Cancer
T3157 COH29
COH29 is an orally available, aromatically substituted thiazole and inhibitor of the human... Cancer
T3110 PRT 4165
Inhibitor of Bmi1/Ring1A, subunits of the polycomb repressive complex 1 (PRC1); inhibits s... Others
T3134 Mirin
Mirin is a potent Mre11–Rad50–Nbs1 (MRN) complex inhibitor, and inhibits Mre11-associated ... Others
T3649 BGP-15
BGP-15 is a?PARP?inhibitor which has protective effect after schemia reperfusion injury Metabolism
T3654 APY29
APY29 is an allosteric modulator of IRE1α; inhibits IRE1α autophosphorylation (IC50 = 280 ... Others
T7004 Tubercidin
Tubercidin, an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA... Others
T6984 SirReal2
SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM. Others
T6974 Saccharin 1-methylimidazole (SMI)
SMI is considered a general-purpose activator for DNA and RNA synthesis. Others
T6970 RK-33
RK-33 is a first-in-class small molecule inhibitor of DDX3 (a RNA helicase) and causes G1 ... Others
T6967 RHPS4
RHPS4 is a potent inhibitor of Telomerase at submicromolar. Others
T6942 Picolinamide
Picolinamide is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei f... Others
T6912 NU1025
NU1025 is a potent PARP inhibitor with IC50 of 400 nM. Others
T6892 MK-4827(Niraparib) tosylate
MK-4827(Niraparib) tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.... Others
T6890 Mitomycin C
Mitomycin C?is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat dif... Others
T6865 Quisinostat (JNJ-26481585) 2HCl
Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest p... Others
T6856 Halofuginone
Halofuginone is the competitively inhibitor of prolyl-tRNA synthetase with Ki of 18.3 nM.I... Others
T6842 G007-LK
G007-LK is a potent and selective tankyrase inhibitor with IC50 of 46 nM and 25 nM for TNK... Others
T6833 Favipiravir (T-705)
Favipiravir (T-705) is a potent and selective RNA-dependent RNA polymerase inhibitor, used... Others
T6823 E3330
E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-bin... Others
T6801 CeMMEC13
CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC... Others
T6794 Bromodeoxyuridine (BrdU)
Bromodeoxyuridine (BrdU) is a nucleoside analog that competes with thymidine for incorpora... Others
T6780 Benzamide
Benzamide, an inhibitor of poly(ADP-ribose) polymerase, is a derivative of benzoic acid. Others
T6770 AZD0156
AZD0156 is a potent and selective inhibitors of ATM kinase, with potential chemo-/radio-se... Others
T6746 6-Thio-dG
6-thio-dG is a nucleoside analog and telomerase substrate. Others
T3375new Verbascoside
Verbascoside has an antimicrobial activity, notably against Staphylococcus aureus. It can ... Others
T3400new Bakuchiol
Bakuchiol possesses anti-tumor,and anti-helmenthic properties. It has cytotoxic activity, ... Cancer
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