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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 μg | $365 | 35 days | |
50 μg | $695 | 35 days | |
100 μg | $1,310 | 35 days |
Description | (±)18-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid. When formed by the CYP2E1 isoform, 18-HETE is comprised 100% of the (R) isomer. 18(R)-HETE dose-dependently stimulates vasodilation of the rabbit kidney, whereas 18(S)-HETE does not affect perfusion pressure. 18-HETE has negligible effects on ATPase activity. 18(R)-HETE at 1 μM completely blocks 20-HETE-induced vasoconstriction of renal arterioles. |
Molecular Weight | 320.473 |
Formula | C20H32O3 |
Cas No. | 133268-58-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | PBS (pH 7.2): 0.8 mg/mL DMF: Miscible Ethanol: Miscible DMSO: Miscible 0.1 M Na2CO3: 2 mg/mL |
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