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(R,R)-CXCR2-IN-2

Name: (R,R)-CXCR2-IN-2
Brand: TargetMol
SKU: T36443
Rating: 4.5 (1 reviews)

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Catalog No. T36443Cas No. 1838123-22-0

Alias (R,R)-CXCR2-IN-2

(R,R)-CXCR2-IN-2, a diastereoisomer of CXCR2-IN-2 (compound 68), is a brain-penetrant CXCR2 antagonist with a pIC50 of 9 in the Tango assay and 6.8 in the HWB Gro-α induced CD11b expression assay[1].

(R,R)-CXCR2-IN-2

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Catalog No. T36443Alias (R,R)-CXCR2-IN-2Cas No. 1838123-22-0

Pack Size	Price	Availability
25 mg	$1,900	8-10 weeks
50 mg	$2,480	8-10 weeks
100 mg	$3,700	8-10 weeks

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	(R,R)-CXCR2-IN-2, a diastereoisomer of CXCR2-IN-2 (compound 68), is a brain-penetrant CXCR2 antagonist with a pIC50 of 9 in the Tango assay and 6.8 in the HWB Gro-α induced CD11b expression assay[1].
Alias	(R,R)-CXCR2-IN-2

Chemical Properties

Molecular Weight	414.9
Formula	C₁₈H₂₃ClN₂O₅S
Cas No.	1838123-22-0

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 220 mg/mL (530.25 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4102 mL	12.0511 mL	24.1022 mL	120.5110 mL
5 mM	0.4820 mL	2.4102 mL	4.8204 mL	24.1022 mL
10 mM	0.2410 mL	1.2051 mL	2.4102 mL	12.0511 mL
20 mM	0.1205 mL	0.6026 mL	1.2051 mL	6.0255 mL
50 mM	0.0482 mL	0.2410 mL	0.4820 mL	2.4102 mL
100 mM	0.0241 mL	0.1205 mL	0.2410 mL	1.2051 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

(R,R) CXCR2 IN 2(R,R)CXCR2IN2(R,R)-CXCR-2-IN-2CXCR2-IN-2