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GV-150013X

Catalog No. T27503L CAS 151386-96-8

Synonyms: (S)-1-(1-(adamantan-1-ylmethyl)-2,4-dioxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-3-phenylurea

GV-150013X is a potent CCKB antiagonist, pKi= 9.02.

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GV-150013X, CAS 151386-96-8

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	GV-150013X is a potent CCKB antiagonist, pKi= 9.02.
Targets&IC50	CCKB:9.02 (Ki)

Synonyms	(S)-1-(1-(adamantan-1-ylmethyl)-2,4-dioxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-3-phenylurea
Molecular Weight	534.65
Formula	C33H34N4O3
CAS No.	151386-96-8

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 9 mg/mL (16.83 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Gabriella, Finizia, and, et al. Synthesis and evaluation of novel 1,5-Benzodiazepines as potent and selective CCK-B ligands. Effect of the substitution of the N-5 phenyl with alkyl groups[J]. Bioorganic & Medicinal Chemistry Letters, 1996.

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

GV-150013X 151386-96-8 GPCR/G Protein cholecystokinin (S)-1-(1-(adamantan-1-ylmethyl)-2,4-dioxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-3-phenylurea Inhibitor inhibitor inhibit

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