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β-Catenin modulator-7
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Catalog No. T89563Cas No. 2892294-93-6
β-Cateninmodulator-7 (Compound 5) acts as a regulator of β-catenin. It suppresses the expression of β-catenin in both the cytoplasm and nucleus of HCT-116 cells and inhibits the phosphorylation of GSK 3β. Additionally, β-Cateninmodulator-7 facilitates the release of NO in HCT-116 cells and inhibits the proliferation of these cancer cells, with an IC50 value of 0.6-0.9 μM. This compound is utilized in research related to colon cancer.
β-Catenin modulator-7
😃Good
Catalog No. T89563Cas No. 2892294-93-6
β-Cateninmodulator-7 (Compound 5) acts as a regulator of β-catenin. It suppresses the expression of β-catenin in both the cytoplasm and nucleus of HCT-116 cells and inhibits the phosphorylation of GSK 3β. Additionally, β-Cateninmodulator-7 facilitates the release of NO in HCT-116 cells and inhibits the proliferation of these cancer cells, with an IC50 value of 0.6-0.9 μM. This compound is utilized in research related to colon cancer.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks |
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Chemical Properties
| Description | β-Cateninmodulator-7 (Compound 5) acts as a regulator of β-catenin. It suppresses the expression of β-catenin in both the cytoplasm and nucleus of HCT-116 cells and inhibits the phosphorylation of GSK 3β. Additionally, β-Cateninmodulator-7 facilitates the release of NO in HCT-116 cells and inhibits the proliferation of these cancer cells, with an IC50 value of 0.6-0.9 μM. This compound is utilized in research related to colon cancer. |
| Molecular Weight | 583.03 |
| Formula | C26H35ClN4O9 |
| Cas No. | 2892294-93-6 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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