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16-phenoxy tetranor Prostaglandin F2α methyl ester

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Catalog No. T37937Cas No. 51638-90-5
Alias 16-phenoxy tetranor Prostaglandin F2α methyl ester

Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostaglandin F2α (16-phenoxy tetranor PGF2α) is a metabolically stable form of PGF2α containing a 16-phenoxy group at the ω-terminus. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α. 16-phenoxy tetranor PGF2α methyl ester is a lipophilic analog of 16-phenoxy tetranor PGF2α. Methyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.

16-phenoxy tetranor Prostaglandin F2α methyl ester

16-phenoxy tetranor Prostaglandin F2α methyl ester

😃Good
Catalog No. T37937Alias 16-phenoxy tetranor Prostaglandin F2α methyl esterCas No. 51638-90-5
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostaglandin F2α (16-phenoxy tetranor PGF2α) is a metabolically stable form of PGF2α containing a 16-phenoxy group at the ω-terminus. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α. 16-phenoxy tetranor PGF2α methyl ester is a lipophilic analog of 16-phenoxy tetranor PGF2α. Methyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.
Pack SizePriceAvailabilityQuantity
500 μgTBD35 days
1 mgTBD35 days
5 mgTBD35 days
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Product Introduction

Bioactivity
Description
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostaglandin F2α (16-phenoxy tetranor PGF2α) is a metabolically stable form of PGF2α containing a 16-phenoxy group at the ω-terminus. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α. 16-phenoxy tetranor PGF2α methyl ester is a lipophilic analog of 16-phenoxy tetranor PGF2α. Methyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.
Alias16-phenoxy tetranor Prostaglandin F2α methyl ester
Chemical Properties
Molecular Weight404.503
FormulaC23H32O6
Cas No.51638-90-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (247.22 mM), Sonication is recommended.
Ethanol: 100 mg/mL (247.22 mM), Sonication is recommended.
PBS (pH 7.2): 0.5 mg/mL (1.24 mM), Sonication is recommended.
DMF: 100 mg/mL (247.22 mM), Sonication is recommended.
Solution Preparation Table
PBS (pH 7.2)/DMSO/Ethanol/DMF
1mg5mg10mg50mg
1 mM2.4722 mL12.3608 mL24.7217 mL123.6085 mL
DMSO/Ethanol/DMF
1mg5mg10mg50mg
5 mM0.4944 mL2.4722 mL4.9443 mL24.7217 mL
10 mM0.2472 mL1.2361 mL2.4722 mL12.3608 mL
20 mM0.1236 mL0.6180 mL1.2361 mL6.1804 mL
50 mM0.0494 mL0.2472 mL0.4944 mL2.4722 mL
100 mM0.0247 mL0.1236 mL0.2472 mL1.2361 mL

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