Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BAA473 is a bile acid analog that is a potent activator of the pyrin inflammasome. BAA473 can induce secretion of interleukin-18 (IL-18) through activation of the inflammasome in both myeloid and intestinal epithelial cells [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 1,520.00 | |
50 mg | 10-14 weeks | $ 1,980.00 | |
100 mg | 10-14 weeks | $ 2,500.00 |
Description | BAA473 is a bile acid analog that is a potent activator of the pyrin inflammasome. BAA473 can induce secretion of interleukin-18 (IL-18) through activation of the inflammasome in both myeloid and intestinal epithelial cells [1]. |
In vitro | BAA473 (0-33 µM; 24 hours; THP-1-Cas9 cells) treatment induces LPS-primed cell death in THP-1-Cas9 cells. [1]. Cell Viability Assay [1] Cell Line: THP-1-Cas9 cells Concentration: 0 μM, 0.1 μM, 0.4 μM, 1.2 μM, 3.7 μM, 11 μM, 33 μM Incubation Time: 24 hours Result: Induced cell death. |
Molecular Weight | 574.87 |
Formula | C36H62O5 |
CAS No. | T10447 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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BAA473 T10447 Others BAA-473 BAA 473 inhibitor inhibit