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Description | Biotin-PEG2-NHS ester is a biotinylated, polyethylene glycol (PEG)-based linker, which is utilized in PROTAC synthesis for the purpose of biotin attachment[1]. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 500.57 |
Formula | C21H32N4O8S |
Cas No. | 596820-83-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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