store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ly93 is a selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor (IC50: 91 nM) for the study of atherosclerosis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 88.00 | |
5 mg | In stock | $ 148.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 152.00 |
Description | Ly93 is a selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor (IC50: 91 nM) for the study of atherosclerosis. |
In vivo | Pharmacokinetic characterization of Ly93 conducted in C57BL/6J mice suggests oral efficacy of Ly93. As an effective selective SMS2 inhibitor, Ly93 (100 mg/kg, i.g. once daily for 7 days) significantly reduced plasma SM levels in C57BL/6J mice[1]. |
Molecular Weight | 332.4 |
Formula | C21H20N2O2 |
CAS No. | 1883528-69-5 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 80 mg/mL (240.67 mM), Sonification is recommeded.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Ly93 1883528-69-5 Others Ly-93 inhibitor inhibit