Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1. Protostemonine has anti-inflammatory activity, it effectively attenuates LPS-induced inflammatory responses in vitro and in vivo; the beneficial effects are associated with the decreased phosphorylation of MAPK and AKT and the reduced expression of pro-inflammatory mediators, such as iNOS, NO and cytokines. 2. Protostemonine shows strong nematicidal activity against Panagrellus redivevus, with the IC50 value of 0.10 uM. 3. Protostemonine attenuates LPS/GalN-induced acute liver failure and upregulating HO-1 expression is implicated in its hepatoprotective activity. 4. Protostemonine shows significant antitussive activity in a citric acid-induced guinea pig cough model following peripheral administration.
Pack Size | Availability | Price/USD | Quantity |
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10 mg | Inquiry | $ 3,180.00 |
Description | 1. Protostemonine has anti-inflammatory activity, it effectively attenuates LPS-induced inflammatory responses in vitro and in vivo; the beneficial effects are associated with the decreased phosphorylation of MAPK and AKT and the reduced expression of pro-inflammatory mediators, such as iNOS, NO and cytokines. 2. Protostemonine shows strong nematicidal activity against Panagrellus redivevus, with the IC50 value of 0.10 uM. 3. Protostemonine attenuates LPS/GalN-induced acute liver failure and upregulating HO-1 expression is implicated in its hepatoprotective activity. 4. Protostemonine shows significant antitussive activity in a citric acid-induced guinea pig cough model following peripheral administration. |
Source |
Molecular Weight | 417.5 |
Formula | C23H31NO6 |
CAS No. | 27495-40-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble
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Protostemonine 27495-40-5 Others inhibitor inhibit