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Raluridine

Name: Raluridine
Brand: TargetMol
SKU: T19689
Rating: 4.5 (1 reviews)

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Catalog No. T19689Cas No. 119644-22-3

Alias FddClUrd, FCU, DRG-0215, BW-935U-83, 935U-83

Raluridine is a RNA-directed DNA polymerase inhibitor potentially for the treatment of HIV infection. 935U83 inhibited virus growth with an average 50% inhibitory concentration (IC50: 1.8 microM) corresponding IC50s were 0.10 microM for FLT (3'-deoxy-3'-fluorothymidine) and 0.23, 0.49, and 0.03 microM for the approved agents AZT, ddI (2',3'-dideoxyinosine), and ddC (2',3'-dideoxycytosine), respectively.

Raluridine

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Catalog No. T19689Alias FddClUrd, FCU, DRG-0215, BW-935U-83, 935U-83Cas No. 119644-22-3

Pack Size	Price	Availability
25 mg	1.871 €	8-10 weeks
50 mg	2.451 €	8-10 weeks
100 mg	3.230 €	8-10 weeks

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Raluridine is a RNA-directed DNA polymerase inhibitor potentially for the treatment of HIV infection. 935U83 inhibited virus growth with an average 50% inhibitory concentration (IC50: 1.8 microM) corresponding IC50s were 0.10 microM for FLT (3'-deoxy-3'-f
Alias	FddClUrd, FCU, DRG-0215, BW-935U-83, 935U-83

Chemical Properties

Molecular Weight	264.64
Formula	C₉H₁₀ClFN₂O₄
Cas No.	119644-22-3
Relative Density.	1.61 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: Soluble

H2O: 50 mg/mL (188.94 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	3.7787 mL	18.8936 mL	37.7872 mL	188.9359 mL
5 mM	0.7557 mL	3.7787 mL	7.5574 mL	37.7872 mL
10 mM	0.3779 mL	1.8894 mL	3.7787 mL	18.8936 mL
20 mM	0.1889 mL	0.9447 mL	1.8894 mL	9.4468 mL
50 mM	0.0756 mL	0.3779 mL	0.7557 mL	3.7787 mL
100 mM	0.0378 mL	0.1889 mL	0.3779 mL	1.8894 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

RaluridineDRG0215DRG 0215