Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Raluridine is a RNA-directed DNA polymerase inhibitor potentially for the treatment of HIV infection. 935U83 inhibited virus growth with an average 50% inhibitory concentration (IC50: 1.8 microM) corresponding IC50s were 0.10 microM for FLT (3'-deoxy-3'-fluorothymidine) and 0.23, 0.49, and 0.03 microM for the approved agents AZT, ddI (2',3'-dideoxyinosine), and ddC (2',3'-dideoxycytosine), respectively.
Description | Raluridine is a RNA-directed DNA polymerase inhibitor potentially for the treatment of HIV infection. 935U83 inhibited virus growth with an average 50% inhibitory concentration (IC50: 1.8 microM) corresponding IC50s were 0.10 microM for FLT (3'-deoxy-3'-fluorothymidine) and 0.23, 0.49, and 0.03 microM for the approved agents AZT, ddI (2',3'-dideoxyinosine), and ddC (2',3'-dideoxycytosine), respectively. |
Synonyms | DRG-0215, FddClUrd, FCU, 935U-83, BW-935U-83 |
Molecular Weight | 264.64 |
Formula | C9H10ClFN2O4 |
CAS No. | 119644-22-3 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: Soluble
H2O: 50mg/ml(446mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Raluridine 119644-22-3 DRG-0215 FddClUrd FCU 935U-83 BW-935U-83 Inhibitor inhibitor inhibit