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Raluridine

Raluridine
Raluridine is a RNA-directed DNA polymerase inhibitor potentially for the treatment of HIV infection. 935U83 inhibited virus growth with an average 50% inhibitory concentration (IC50: 1.8 microM) corresponding IC50s were 0.10 microM for FLT (3'-deoxy-3'-fluorothymidine) and 0.23, 0.49, and 0.03 microM for the approved agents AZT, ddI (2',3'-dideoxyinosine), and ddC (2',3'-dideoxycytosine), respectively.
Catalog No. T19689Cas No. 119644-22-3

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Raluridine

Catalog No. T19689Alias FddClUrd, FCU, DRG-0215, BW-935U-83, 935U-83Cas No. 119644-22-3

Raluridine is a RNA-directed DNA polymerase inhibitor potentially for the treatment of HIV infection. 935U83 inhibited virus growth with an average 50% inhibitory concentration (IC50: 1.8 microM) corresponding IC50s were 0.10 microM for FLT (3'-deoxy-3'-fluorothymidine) and 0.23, 0.49, and 0.03 microM for the approved agents AZT, ddI (2',3'-dideoxyinosine), and ddC (2',3'-dideoxycytosine), respectively.
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Pack SizePriceAvailabilityQuantity
25 mg$1,9708-10 weeks
50 mg$2,5808-10 weeks
100 mg$3,4008-10 weeks
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Product Introduction

Bioactivity
Description
Raluridine is a RNA-directed DNA polymerase inhibitor potentially for the treatment of HIV infection. 935U83 inhibited virus growth with an average 50% inhibitory concentration (IC50: 1.8 microM) corresponding IC50s were 0.10 microM for FLT (3'-deoxy-3'-f
AliasFddClUrd, FCU, DRG-0215, BW-935U-83, 935U-83
Chemical Properties
Molecular Weight264.64
FormulaC9H10ClFN2O4
Cas No.119644-22-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: Soluble
H2O: 50 mg/mL (446 mM)
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM3.7787 mL18.8936 mL37.7872 mL188.9359 mL
5 mM0.7557 mL3.7787 mL7.5574 mL37.7872 mL
10 mM0.3779 mL1.8894 mL3.7787 mL18.8936 mL
20 mM0.1889 mL0.9447 mL1.8894 mL9.4468 mL
50 mM0.0756 mL0.3779 mL0.7557 mL3.7787 mL
100 mM0.0378 mL0.1889 mL0.3779 mL1.8894 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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