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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Thiol-PEG3-Boc, a PEG-based linker for PROTACs, connects two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands linked together: one binding to an E3 ubiquitin ligase and the other to the target protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Alias | Thiol-PEG3-t-butyl ester |
Molecular Weight | 294.41 |
Formula | C13H26O5S |
Cas No. | 1446282-39-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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