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AKT-IN-14

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Catalog No. T85614Cas No. 2781918-35-0

AKT-IN-14 (Example 2), a potent inhibitor of AKT, demonstrates IC50 values of <0.01 nM for AKT1, 1.06 nM for AKT2, and 0.66 nM for AKT3. It is applicable in the field of cancer research [1].

AKT-IN-14
Other Forms of AKT-IN-14:
AKT-IN-14 free baseT856132781918-27-0
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AKT-IN-14

😃Good
Catalog No. T85614Cas No. 2781918-35-0
AKT-IN-14 (Example 2), a potent inhibitor of AKT, demonstrates IC50 values of <0.01 nM for AKT1, 1.06 nM for AKT2, and 0.66 nM for AKT3. It is applicable in the field of cancer research [1].
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10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
AKT-IN-14 (Example 2), a potent inhibitor of AKT, demonstrates IC50 values of <0.01 nM for AKT1, 1.06 nM for AKT2, and 0.66 nM for AKT3. It is applicable in the field of cancer research [1].
Chemical Properties
Molecular Weight543.86
FormulaC22H22BrClF2N4OS
Cas No.2781918-35-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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