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Anti-B2M Monoclonal Antibody-PE is a Biotin-conjugated rabbit antibody targeting B2M. Anti-B2M Monoclonal Antibody-PE can be used in ELISA, FACS.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 μg | $345 | 12 days | |
50 μg | $575 | 12 days | |
100 μg | $865 | 12 days |
Description | Anti-B2M Monoclonal Antibody-PE is a Biotin-conjugated rabbit antibody targeting B2M. Anti-B2M Monoclonal Antibody-PE can be used in ELISA, FACS. |
Alias | Beta-2-microglobulin |
Ig Type | Rabbit monoclonal IgG |
Reactivity | Human |
Verified Activity | Flow cytometry analysis of B2M overexpressed 406F cells with TMAZ-0010P, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
Application | ELISA, FACS |
Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Subcellular Localization | Secreted |
Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of B2M protein. |
Purification | Protein A Affinity Purified |
Appearance | Liquid |
Formulation | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
Purity | > 95% as determined by SDS-PAGE. |
Research Background | Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed: 25356553) |
Conjucates | PE |
Others Formats | Biotin/APC/AF488/AF555/AF647 |
Antibody Types Available | 2 |
Immunogen | B2M |
Antigen Species | Human |
Gene ID | 567 |
Uniprot ID | |
Biology Area | Immunology Research |
Molecular Weight | 150 kDa |
Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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