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Anti-B2M Monoclonal Antibody-PE

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Catalog No. TMAZ-0010P
Alias Beta-2-microglobulin

Anti-B2M Monoclonal Antibody-PE is a Biotin-conjugated rabbit antibody targeting B2M. Anti-B2M Monoclonal Antibody-PE can be used in ELISA, FACS.

Anti-B2M Monoclonal Antibody-PE

Anti-B2M Monoclonal Antibody-PE

😃Good
Catalog No. TMAZ-0010PAlias Beta-2-microglobulin
Anti-B2M Monoclonal Antibody-PE is a Biotin-conjugated rabbit antibody targeting B2M. Anti-B2M Monoclonal Antibody-PE can be used in ELISA, FACS.
Pack SizePriceAvailabilityQuantity
25 μg327 €12 days
50 μg546 €12 days
100 μg821 €12 days
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Product Introduction

Bioactivity
Description
Anti-B2M Monoclonal Antibody-PE is a Biotin-conjugated rabbit antibody targeting B2M. Anti-B2M Monoclonal Antibody-PE can be used in ELISA, FACS.
AliasBeta-2-microglobulin
Ig Type
Rabbit monoclonal IgG
Reactivity
Human
Verified Activity
Flow cytometry analysis of B2M overexpressed 406F cells with TMAZ-0010P, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
Application
ELISA, FACS
Recommended Dose
0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted
ConstructionThis antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of B2M protein.
PurificationProtein A Affinity Purified
AppearanceLiquid
Formulation0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin.
Purity> 95% as determined by SDS-PAGE.
Research BackgroundComponent of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed: 25356553)
Related Conjugates and Formulations
Conjucates
PE
Others Formats
Biotin/APC/AF488/AF555/AF647
Antibody Types Available
2
Antigen Details
Immunogen
B2M
Antigen Species
Human
Gene ID
567
Uniprot ID
Biology Area
Immunology Research
Chemical Properties
Molecular Weight150 kDa
Stability & Storage
Stability & StorageFor unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze.
TransportFor unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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