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Anti-CHGA Monoclonal Antibody-PE
Anti-CHGA Monoclonal Antibody-PE
Anti-CHGA Monoclonal Antibody-PE is a Biotin-conjugated rabbit antibody targeting CHGA. Anti-CHGA Monoclonal Antibody-PE can be used in ELISA, FACS.
Catalog No. TMAZ-0139P
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Anti-CHGA Monoclonal Antibody-PE
Catalog No. TMAZ-0139PAlias Pituitary secretory protein I, Chromogranin-A
Anti-CHGA Monoclonal Antibody-PE is a Biotin-conjugated rabbit antibody targeting CHGA. Anti-CHGA Monoclonal Antibody-PE can be used in ELISA, FACS.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 μg | $385 | 12 days | |
| 50 μg | $640 | 12 days | |
| 100 μg | $960 | 12 days |
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CHGA Monoclonal Antibody-PE is a Biotin-conjugated rabbit antibody targeting CHGA. Anti-CHGA Monoclonal Antibody-PE can be used in ELISA, FACS. |
| Alias | Pituitary secretory protein I, Chromogranin-A |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of CHGA overexpressed 486F cells with TMAZ-0139P, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | ELISA, FACS |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Single-pass type I membrane |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of CHGA protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Strongly inhibits glucose induced insulin release from the pancreas|Inhibits catecholamine release from chromaffin cells and noradrenergic neurons by acting as a non-competitive nicotinic cholinergic antagonist (PubMed: 15326220). Displays antibacterial activity against Gram-positive bacteria S.aureus and M.luteus, and Gram-negative bacteria E.coli and P.aeruginosa (PubMed: 15723172, PubMed: 24723458). Can induce mast cell migration, degranulation and production of cytokines and chemokines (PubMed: 21214543). Acts as a potent scavenger of free radicals in vitro (PubMed: 24723458). May play a role in the regulation of cardiac function and blood pressure (PubMed: 18541522)|Regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation |
| Conjucates | PE |
| Others Formats | Biotin/APC/AF488/AF555/AF647 |
| Antibody Types Available | 1 |
| Immunogen | CHGA |
| Antigen Species | Human |
| Gene ID | 1113 |
| Uniprot ID | |
| Biology Area | Cancer Research |
| Molecular Weight | 150 kDa |
Stability & Storage
| Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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