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Anti-CXADR Monoclonal Antibody-APC
Catalog No. TMAZ-0258A
Alias HCVADR, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, Coxsackievirus and adenovirus receptor
Anti-CXADR Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting CXADR. Anti-CXADR Monoclonal Antibody-APC can be used in ELISA, FACS.
Anti-CXADR Monoclonal Antibody-APC
Anti-CXADR Monoclonal Antibody-APC
Catalog No. TMAZ-0258AAlias HCVADR, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, Coxsackievirus and adenovirus receptor
Anti-CXADR Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting CXADR. Anti-CXADR Monoclonal Antibody-APC can be used in ELISA, FACS.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 μg | $570 | 12 days | |
| 50 μg | $945 | 12 days | |
| 100 μg | $1,415 | 12 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CXADR Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting CXADR. Anti-CXADR Monoclonal Antibody-APC can be used in ELISA, FACS. |
| Alias | HCVADR, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, Coxsackievirus and adenovirus receptor |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of CXADR overexpressed 463F cells with TMAZ-0258A, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | ELISA, FACS |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of CXADR protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair|(Microbial infection) Acts as a receptor for adenovirus type C|(Microbial infection) Acts as a receptor for Coxsackievirus B1 to B6 |
| Conjucates | APC |
| Others Formats | Biotin/PE/AF488/AF555/AF647 |
| Antibody Types Available | 1 |
| Immunogen | CXADR |
| Antigen Species | Human |
| Gene ID | 1525 |
| Uniprot ID | |
| Biology Area | Other Functions |
| Molecular Weight | 150 kDa |
Stability & Storage
| Stability & Storage | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| Transport | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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