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Anti-CXADR Monoclonal Antibody-APC

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Catalog No. TMAZ-0258A
Alias HCVADR, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, Coxsackievirus and adenovirus receptor

Anti-CXADR Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting CXADR. Anti-CXADR Monoclonal Antibody-APC can be used in ELISA, FACS.

Anti-CXADR Monoclonal Antibody-APC

Anti-CXADR Monoclonal Antibody-APC

😃Good
Catalog No. TMAZ-0258AAlias HCVADR, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, Coxsackievirus and adenovirus receptor
Anti-CXADR Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting CXADR. Anti-CXADR Monoclonal Antibody-APC can be used in ELISA, FACS.
Pack SizePriceAvailabilityQuantity
25 μg541 €12 days
50 μg897 €12 days
100 μg1.344 €12 days
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Product Introduction

Bioactivity
Description
Anti-CXADR Monoclonal Antibody-APC is a Biotin-conjugated rabbit antibody targeting CXADR. Anti-CXADR Monoclonal Antibody-APC can be used in ELISA, FACS.
AliasHCVADR, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, Coxsackievirus and adenovirus receptor
Ig Type
Rabbit monoclonal IgG
Reactivity
Human
Verified Activity
Flow cytometry analysis of CXADR overexpressed 463F cells with TMAZ-0258A, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
Application
ELISA, FACS
Recommended Dose
0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted
ConstructionThis antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of CXADR protein.
PurificationProtein A Affinity Purified
AppearanceLiquid
Formulation0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin.
Purity> 95% as determined by SDS-PAGE.
Research BackgroundComponent of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair|(Microbial infection) Acts as a receptor for adenovirus type C|(Microbial infection) Acts as a receptor for Coxsackievirus B1 to B6
Related Conjugates and Formulations
Conjucates
APC
Others Formats
Biotin/PE/AF488/AF555/AF647
Antibody Types Available
1
Antigen Details
Immunogen
CXADR
Antigen Species
Human
Gene ID
1525
Uniprot ID
Biology Area
Other Functions
Chemical Properties
Molecular Weight150 kDa
Stability & Storage
Stability & StorageFor unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze.
TransportFor unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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